The Human Carbonic Anhydrase II in Platelets: An Underestimated Field of Its Activity
Joint Authors
Szahidewicz-Krupska, E.
Doroszko, A.
Jakubowski, Maciej
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-28
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Carbonic anhydrases constitute a group of enzymes that catalyse reversible hydration of carbon dioxide leading to the formation of bicarbonate and proton.
The platelet carbonic anhydrase II (CAII) was described for the first time in the '80s of the last century.
Nevertheless, its direct role in platelet physiology and pathology still remains poorly understood.
The modulation of platelet CAII action as a therapeutic approach holds promise as a novel strategy to reduce the impact of cardiovascular diseases.
This short review paper summarises the current knowledge regarding the role of human CAII in regulating platelet function.
The potential future directions considering this enzyme as a potential drug target and important pathophysiological chain in platelet-related disorders are described.
American Psychological Association (APA)
Jakubowski, Maciej& Szahidewicz-Krupska, E.& Doroszko, A.. 2018. The Human Carbonic Anhydrase II in Platelets: An Underestimated Field of Its Activity. BioMed Research International،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1126733
Modern Language Association (MLA)
Jakubowski, Maciej…[et al.]. The Human Carbonic Anhydrase II in Platelets: An Underestimated Field of Its Activity. BioMed Research International No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1126733
American Medical Association (AMA)
Jakubowski, Maciej& Szahidewicz-Krupska, E.& Doroszko, A.. The Human Carbonic Anhydrase II in Platelets: An Underestimated Field of Its Activity. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1126733
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126733