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Evaluation of Regional Variability and Measurement Reproducibility of Intravoxel Incoherent Motion Diffusion Weighted Imaging Using a Cardiac Stationary Phase Based ECG Trigger Method
Joint Authors
Xiang, Zhiming
Ai, Zhu
Liang, Jianke
Li, Guijin
Zhu, Xiaolei
Yan, Xu
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-17
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Purpose.
To evaluate the performance of an optimized ECG trigger diffusion weighted imaging (DWI) sequence in liver and its application in liver disease.
Materials and Methods.
Eighteen healthy volunteers underwent intravoxel incoherent motion diffusion weighted imaging (IVIM-DWI) scan of the liver twice in 1.5T MR scanner with signed informed consent approved by local ethic committees.
A new method, called cardiac stationary phase based ECG trigger (CaspECG), and FB method were applied.
The apparent diffusion coefficient (ADC) and the IVIM parameters, including pure diffusion coefficient ( D ), perfusion-related diffusion coefficient ( D ⁎ ), and perfusion fraction, (PF) were calculated, and then 18 region of interests were drawn on these parameter maps independently by two readers through whole hepatic lobe.
The regional variability and reproducibility between two repeated scans were evaluated using interclass correlation coefficients (ICCs) and Bland-Altman plot, respectively, and compared between the CaspECG and FB methods.
The signal-to-noise ratio (SNR) of DWI data was also evaluated.
Result.
Compared to the FB method, the proposed CaspECG method showed significant higher SNRs in DWI data, lower regional variability between left and right hepatic lobes, and higher reproducibility of ADC, PF, D, and D ⁎ between repeat scans [left lobe, limit of agreement (LOA) of Bland-Altman plot: 10.1%, 18.3%, 19.8%, and 59.2%; right lobe, LOA: 10.25%, 14.15%, 16.45%, and 39.45%].
D ⁎ showed the worst reproducibility in all parameters.
Conclusion.
The novel CaspECG method outperformed the FB method in compensating the cardiac motion induced artifacts in DWI data and generating more reliable quantitative parameters, with less regional variability and higher repeatability, especially in the left hepatic lobe.
American Psychological Association (APA)
Xiang, Zhiming& Ai, Zhu& Liang, Jianke& Li, Guijin& Zhu, Xiaolei& Yan, Xu. 2018. Evaluation of Regional Variability and Measurement Reproducibility of Intravoxel Incoherent Motion Diffusion Weighted Imaging Using a Cardiac Stationary Phase Based ECG Trigger Method. BioMed Research International،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1126779
Modern Language Association (MLA)
Xiang, Zhiming…[et al.]. Evaluation of Regional Variability and Measurement Reproducibility of Intravoxel Incoherent Motion Diffusion Weighted Imaging Using a Cardiac Stationary Phase Based ECG Trigger Method. BioMed Research International No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1126779
American Medical Association (AMA)
Xiang, Zhiming& Ai, Zhu& Liang, Jianke& Li, Guijin& Zhu, Xiaolei& Yan, Xu. Evaluation of Regional Variability and Measurement Reproducibility of Intravoxel Incoherent Motion Diffusion Weighted Imaging Using a Cardiac Stationary Phase Based ECG Trigger Method. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1126779
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126779