Evaluation of Automatic Blood Analyzer as Screening Method in Fetomaternal Hemorrhage
Joint Authors
Barini, Ricardo
Cardoso, Marcella R.
Souza-Araújo, Caroline N. de
Talarico, Maria Cecília R.
Heinrich-Mouçouçah, Juliana
Guimarães, Fernando
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Screening of fetomaternal hemorrhage (FMH) is essential in management of fetomaternal antigen incompatibilities of blood.
The objective in this study was to evaluate the ability of automatic blood analyzer (ABA) to screen FMH, also comparing this method with flow cytometry (FCM).
The contents of fetal red blood cells and fetal hemoglobin were evaluated by FCM and ABA, respectively, using both blood samples of male adults laced with umbilical cord blood diluted at 1/10, 1/100, 1/1,000, and 1/10,000, or blood from puerperal women collected within 48 hours following delivery.
FCM had better performance (area under curve, AUC = 0.8723) than ABA (AUC = 0.6569) in detecting fetal blood laced with blood from male adults.
At a critical level of 0.5%, ABA indicated that 27.5% of puerperal women would have FMH while FCM did not detect FMH.
Our results showed that ABA overestimates FMH and disagrees with FCM on indicating puerperal women with FMH.
ABA is inadequate for being used to screen for or to measure FMH.
American Psychological Association (APA)
Cardoso, Marcella R.& Souza-Araújo, Caroline N. de& Talarico, Maria Cecília R.& Heinrich-Mouçouçah, Juliana& Guimarães, Fernando& Barini, Ricardo. 2019. Evaluation of Automatic Blood Analyzer as Screening Method in Fetomaternal Hemorrhage. BioMed Research International،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1126793
Modern Language Association (MLA)
Cardoso, Marcella R.…[et al.]. Evaluation of Automatic Blood Analyzer as Screening Method in Fetomaternal Hemorrhage. BioMed Research International No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1126793
American Medical Association (AMA)
Cardoso, Marcella R.& Souza-Araújo, Caroline N. de& Talarico, Maria Cecília R.& Heinrich-Mouçouçah, Juliana& Guimarães, Fernando& Barini, Ricardo. Evaluation of Automatic Blood Analyzer as Screening Method in Fetomaternal Hemorrhage. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1126793
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126793