Dioscin Inhibits Virulence Factors of Candida albicans
Joint Authors
Ma, Tonghui
Sui, Yujie
Yang, Longfei
Liu, Xin
Wang, Fang
Zhong, Lili
Quan, Guihua
Huang, Ying
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-26
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Candida albicans infections present a heavy burden upon public health, with only a few drugs available, while biofilms formed by C.
albicans worsen this situation.
Dioscin has antitumor, anti-inflammatory, and hepatoprotective effects, and this study was conducted to evaluate the effects of dioscin on the biofilm formation and development, as well as other virulence factors of C.
albicans such as morphological transition, adhesion, and extracellular secreted phospholipase.
Our results showed dioscin inhibits these virulence factors and has low cytotoxicity against mammalian cells.
Considering protective effects of dioscin against damage on liver and kidney, dioscin may be used as a potential candidate for antifungal development.
American Psychological Association (APA)
Yang, Longfei& Liu, Xin& Zhong, Lili& Sui, Yujie& Quan, Guihua& Huang, Ying…[et al.]. 2018. Dioscin Inhibits Virulence Factors of Candida albicans. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1126832
Modern Language Association (MLA)
Yang, Longfei…[et al.]. Dioscin Inhibits Virulence Factors of Candida albicans. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1126832
American Medical Association (AMA)
Yang, Longfei& Liu, Xin& Zhong, Lili& Sui, Yujie& Quan, Guihua& Huang, Ying…[et al.]. Dioscin Inhibits Virulence Factors of Candida albicans. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1126832
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126832
