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Corneal Thickness Response after Anesthetic Eye Drops: Our Own Results and Meta-Analysis
Joint Authors
Cerviño, Alejandro
Calvo-Maroto, Ana M.
Perez-Bermejo, Marcelino
Moscardo, Monica
Murillo-Llorente, Mayte
Sanchis-Gimeno, Juan A.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-05
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
We aimed to test if there are different patterns in the central corneal thickness (CCT) response after instilling oxybuprocaine anesthetic eye drops and also to determine whether there is a significant change in the CCT.
CCT was measured in 60 eyes of 60 healthy subjects before and during the hour after oxybuprocaine 0.4% eye drops were instilled.
In addition, a systematic review and meta-analysis were carried out in order to answer the following PICO (patient, intervention, comparison, and outcome) question: What effect do anesthetic eye drops have on CCT values? We found no significant changes in the mean CCT values during the hour’s observation (ANOVA, p=0.209), and the meta-analysis revealed no statistically significant changes in the CCT after anesthesia (Q-Value = 1.111; p value = 1.000; I2 = 0.000; Tau2 = 0.000; Stderr = 0.020).
However, we found three CCT response patterns 5 minutes after anesthesia: Pattern 1, subjects with no significant changes in their CCT values (n=14, 46.7%); Pattern 2, subjects with significant CCT increases (n=11, 36.7%); and Pattern 3, subjects with significant CCT decreases (n=5, 16.7%).
In sum, there are no significant changes in the CCT after anesthesia, but there are three different CCT response patterns 5 minutes after anesthesia.
American Psychological Association (APA)
Perez-Bermejo, Marcelino& Cerviño, Alejandro& Calvo-Maroto, Ana M.& Moscardo, Monica& Murillo-Llorente, Mayte& Sanchis-Gimeno, Juan A.. 2018. Corneal Thickness Response after Anesthetic Eye Drops: Our Own Results and Meta-Analysis. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1126879
Modern Language Association (MLA)
Perez-Bermejo, Marcelino…[et al.]. Corneal Thickness Response after Anesthetic Eye Drops: Our Own Results and Meta-Analysis. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1126879
American Medical Association (AMA)
Perez-Bermejo, Marcelino& Cerviño, Alejandro& Calvo-Maroto, Ana M.& Moscardo, Monica& Murillo-Llorente, Mayte& Sanchis-Gimeno, Juan A.. Corneal Thickness Response after Anesthetic Eye Drops: Our Own Results and Meta-Analysis. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1126879
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1126879