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Impact of an In-House Pediatric Surgery Unit and Human Milk Centered Enteral Nutrition on Necrotizing Enterocolitis
Joint Authors
Hensel, Kai O.
Zamrik, Sonja
Giachero, Federica
Heldmann, Michael
Wirth, Stefan
Jenke, Andreas
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-13
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The importance for mortality and morbidity of an in-house pediatric surgery unit for premature infants with necrotizing enterocolitis (NEC) remains undefined.
Data on 389 consecutive very low birth weight infants with a birth weight <1250 g admitted between 2009 and 2014 was retrospectively analyzed in two almost identical neonatal intensive care units.
Epidemiological data (n=172 and n=217, respectively) were comparable.
Incidence of NEC stage II+ was significantly higher in center 1 (15.1 versus 5.5%, n=18 versus 6).
This correlated with a significantly lower rate of exclusive human milk feeding compared to center 2 (24.2 versus 59.3%).
Probiotic treatment did not differ.
Importantly, in case of surgery the length of removed intestine (49.9 versus 19.5 cm) and the rate of severe short-bowel syndrome (38.9 versus 0 %) were significantly higher in center 1 (no in-house pediatric surgery).
Furthermore, long-term morbidity assessment revealed more impaired motoric (-4.2 versus -2.2 months, p=0.21) and psychologic (-4.3 versus -1.6 months, p=0.09) development in center 1.
Mortality was similar in both centers.
Conclusions.
Short- and possibly also long-term morbidity of NEC is clearly associated with the presence of an on-site pediatric surgery unit.
Enteral nutrition with human milk seems to be a strong protective factor against NEC.
American Psychological Association (APA)
Zamrik, Sonja& Giachero, Federica& Heldmann, Michael& Hensel, Kai O.& Wirth, Stefan& Jenke, Andreas. 2018. Impact of an In-House Pediatric Surgery Unit and Human Milk Centered Enteral Nutrition on Necrotizing Enterocolitis. BioMed Research International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1127048
Modern Language Association (MLA)
Zamrik, Sonja…[et al.]. Impact of an In-House Pediatric Surgery Unit and Human Milk Centered Enteral Nutrition on Necrotizing Enterocolitis. BioMed Research International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1127048
American Medical Association (AMA)
Zamrik, Sonja& Giachero, Federica& Heldmann, Michael& Hensel, Kai O.& Wirth, Stefan& Jenke, Andreas. Impact of an In-House Pediatric Surgery Unit and Human Milk Centered Enteral Nutrition on Necrotizing Enterocolitis. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1127048
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127048