A Review on Flavonoid Apigenin: Dietary Intake, ADME, Antimicrobial Effects, and Interactions with Human Gut Microbiota
Joint Authors
Yam, Kit L.
Wang, Minqian
Firrman, Jenni
Liu, LinShu
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-16
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
Apigenin is a flavonoid of low toxicity and multiple beneficial bioactivities.
Published reviews all focused on the findings using eukaryotic cells, animal models, or epidemiological studies covering the pharmacokinetics, cancer chemoprevention, and drug interactions of apigenin; however, no review is available on the antimicrobial effects of apigenin.
Research proves that dietary apigenin passes through the upper gastrointestinal tract and reaches the colon after consumption.
For that reason, it is worthwhile to study the potential interactions between apigenin and human gut microbiota.
This review summarizes studies on antimicrobial effects of apigenin as well as what has been reported on apigenin and human gut microbiota.
Various levels of effectiveness have been reported on apigenin’s antibacterial, antifungal, and antiparasitic capability.
It has been shown that apigenin or its glycosides are degraded into smaller metabolites by certain gut bacteria which can regulate the human body after absorption.
How apigenin contributes to the structural and functional changes in human gut microbiota as well as the bioactivities of apigenin bacterial metabolites are worth further investigation.
American Psychological Association (APA)
Wang, Minqian& Firrman, Jenni& Liu, LinShu& Yam, Kit L.. 2019. A Review on Flavonoid Apigenin: Dietary Intake, ADME, Antimicrobial Effects, and Interactions with Human Gut Microbiota. BioMed Research International،Vol. 2019, no. 2019, pp.1-18.
https://search.emarefa.net/detail/BIM-1127057
Modern Language Association (MLA)
Wang, Minqian…[et al.]. A Review on Flavonoid Apigenin: Dietary Intake, ADME, Antimicrobial Effects, and Interactions with Human Gut Microbiota. BioMed Research International No. 2019 (2019), pp.1-18.
https://search.emarefa.net/detail/BIM-1127057
American Medical Association (AMA)
Wang, Minqian& Firrman, Jenni& Liu, LinShu& Yam, Kit L.. A Review on Flavonoid Apigenin: Dietary Intake, ADME, Antimicrobial Effects, and Interactions with Human Gut Microbiota. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-18.
https://search.emarefa.net/detail/BIM-1127057
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127057