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High Prevalence of Sarcopenia in HIV-Infected Individuals
Joint Authors
Echeverría, Patricia
Estany, Carla
Ornelas, Arelly
Clotet, Bonaventura
Negredo, Eugenia
Bonjoch, Anna
Puig, Jordi
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-12
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Sarcopenia is a geriatric syndrome that leads to a loss of functionality and mortality.
Methods.
We assessed the prevalence of sarcopenia in HIV-infected patients attended in our HIV Unit who had at least two DXA scans from 2000 to 2016 (1,720 DXA scans from 860 individuals).
Sarcopenia was determinate according to appendicular skeletal muscle mass index (ASM) calculated as the ratio between skeletal muscle mass index (SMI) by DXA and height2 (kg/m2).
We stratified patients by gender and age (<40, 41-50, and >50 years) and according to the interval between DXAs (≤3, 3-7, 7-10, >10 years).
The statistical analysis was performed using SPSS version 19.
Results.
Median (IQR) age was 52 (47; 57) years, and 76% were male.
The median (IQR) time with HIV infection was 8 (3; 15) years.
The prevalence of sarcopenia was 25.7% (95% CI, 22.8-28.7), more prevalent in those aged >50 years (27.8%).
Stratifying by gender, 43% of women aged >50 years presented sarcopenia compared with 8.8% of men.
The frequency of sarcopenia increased from 37.6% to 49.4% when interval between DXA was 7-10 years (n=109), significantly higher in women than in men (p=0.016).
In addition to the traditional risk factors, time with HIV infection was associated with sarcopenia [RR 1.780 (95% CI, 1.314-2.411), p=0.001].
Conclusion.
The prevalence and progression of sarcopenia in HIV-infected patients were high, mainly among women.
Further studies are necessary to assess the best approaches to prevent this condition and its consequences.
American Psychological Association (APA)
Echeverría, Patricia& Bonjoch, Anna& Puig, Jordi& Estany, Carla& Ornelas, Arelly& Clotet, Bonaventura…[et al.]. 2018. High Prevalence of Sarcopenia in HIV-Infected Individuals. BioMed Research International،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1127076
Modern Language Association (MLA)
Echeverría, Patricia…[et al.]. High Prevalence of Sarcopenia in HIV-Infected Individuals. BioMed Research International No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1127076
American Medical Association (AMA)
Echeverría, Patricia& Bonjoch, Anna& Puig, Jordi& Estany, Carla& Ornelas, Arelly& Clotet, Bonaventura…[et al.]. High Prevalence of Sarcopenia in HIV-Infected Individuals. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1127076
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127076