Biomarkers of Acute Kidney Injury after Cardiac Surgery: A Narrative Review
Joint Authors
Yang, Yi
Wu, Binbin
Chen, Jianghua
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-27
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Cardiac surgery-associated acute kidney injury (CSA-AKI) is a major and serious complication in patients undergoing cardiac surgery and is independently associated with perioperative mortality and mortality.
Therapeutic intervention aiming at reversing kidney dysfunction seems disappointing across multiple settings.
Consequently, attention has shifted from treatment to prevention and early detection.
The Kidney Disease: Improving Global Outcomes (KDIGO) guidelines have unified diagnostic standards mainly based on the serum creatinine (Scr) level or urine output, but neither marker is kidney specific.
Efforts have been made to identify novel biomarkers with high sensitivity and specificity.
The diagnostic capabilities of neutrophil gelatinase-associated lipocalin (NGAL) and G1 cell cycle arrest biomarker as biomarkers have been confirmed in a large number of clinical trials.
The utility of biomarkers of cardiac function and inflammation has been validated in clinical studies.
Aiming to offer valuable information for further research, we summarize the progress in defining current markers relevant to CSA-AKI in the last three years.
American Psychological Association (APA)
Wu, Binbin& Chen, Jianghua& Yang, Yi. 2019. Biomarkers of Acute Kidney Injury after Cardiac Surgery: A Narrative Review. BioMed Research International،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1127216
Modern Language Association (MLA)
Wu, Binbin…[et al.]. Biomarkers of Acute Kidney Injury after Cardiac Surgery: A Narrative Review. BioMed Research International No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1127216
American Medical Association (AMA)
Wu, Binbin& Chen, Jianghua& Yang, Yi. Biomarkers of Acute Kidney Injury after Cardiac Surgery: A Narrative Review. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1127216
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127216