Magnetic Resonance Imaging of Chiari Malformation Type I in Adult Patients with Dysphagia
Joint Authors
Jian, Fengzeng
Wu, Hao
Lu, Feng
Chen, Zan
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-14
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To explore the magnetic resonance imaging (MRI) characteristics of Chiari malformation type I (CMI) in patients with dysphagia.
Methods.
Adult patients diagnosed with CMI were retrospectively and consecutively reviewed from January 2013 to December 2016.
Symptoms and medical characteristics were recorded.
According to the clinical manifestations, we divided the patients into two groups.
The first group had 21 patients with symptoms of dysphagia and the second group had 71 patients with nondysphagia symptoms.
Various length or angle measurements of the posterior cranial fossa (PCF), syringomyelia, and degree of cerebellar tonsillar herniation were investigated using magnetic resonance imaging (MRI).
Univariate, correlation, and multivariate logistic regression analyses were used to compare and analyze the data of the two groups.
Results.
The mean length of the clivus, height of PCF, and slope inclination angle of clivus significantly decreased in the dysphagia group compared to the nondysphagia group.
The mean cranial spinal angle (CSA) and degree of cerebellar tonsillar herniation were significantly larger in the dysphagia group.
There were no correlations between the age, sex, disease duration, and the length of cerebellar tonsillar herniation or CSA.
There was a positive correlation between dysphagia level and CSA (r=-0.50; p=0.021).
Among CSA, age, sex, the degree of tonsillar herniation, syringomyelia, and disease duration, CSA was the individual sign that correlated significantly with dysphagia (OR: 1.447; 95% CI: 1.182-1.698; P<0.001).
Interactions between CSA and the degree of cerebellar tonsillar herniation, syringomyelia, and dysphagia existed (OR: 1.104; 95% CI: 1.042-1.170; P=0.001 and OR: 1.081; 95% CI: 1.023-1.142; P=0.006, respectively).
Conclusions.
The CMI patients with dysphagia were more likely to have a large CSA on MRI compared with CMI patients without dysphagia.
An increased probability with syringomyelia or length of cerebellar tonsillar herniation can enhance the contribution of CSA to dysphagia in patients with CMI.
American Psychological Association (APA)
Lu, Feng& Chen, Zan& Wu, Hao& Jian, Fengzeng. 2019. Magnetic Resonance Imaging of Chiari Malformation Type I in Adult Patients with Dysphagia. BioMed Research International،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1127325
Modern Language Association (MLA)
Lu, Feng…[et al.]. Magnetic Resonance Imaging of Chiari Malformation Type I in Adult Patients with Dysphagia. BioMed Research International No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1127325
American Medical Association (AMA)
Lu, Feng& Chen, Zan& Wu, Hao& Jian, Fengzeng. Magnetic Resonance Imaging of Chiari Malformation Type I in Adult Patients with Dysphagia. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1127325
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127325