Relationship of Natriuretic Peptides with Left Atrial Structure and Function within 1 Month after Electrical Cardioversion in Patients with Persistent Atrial Fibrillation
Joint Authors
Karaliute, Rasa
Jureviciute, Justina
Jurgaityte, Julija
Stanaitiene, Giedre
Mizariene, Vaida
Kazakevicius, Tomas
Urboniene, Daiva
Kavoliuniene, Ausra
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Atrial fibrillation (AF) despite the absence of heart failure is related to increased levels of natriuretic peptides (NPs).
NPs have not been widely investigated in relation to left atrium (LA) function after sinus rhythm (SR) restoration and duration of AF.
The aim of the study was to determine the changes of NPs levels and to define their relation with LA phasic function after electrical cardioversion (ECV).
Methods.
The study included 48 persistent AF patients with restored SR after ECV.
NT-proANP and NT-proBNP were measured for all patients before the ECV.
LA phasic function (reservoir, conduit, and pump phases) was assessed using echocardiographic volumetric analysis within the first 24 hours after ECV.
Patients were repeatedly tested after 1 month in case of SR maintenance.
Results.
After 1 month, SR was maintained in 26 (54%) patients.
For those patients, NT-proBNP decreased significantly (p=0.0001), whereas NT-proANP tended to decrease (p=0.13).
Following 1 month after SR restoration, LA indexed volume decreased (p=0.0001) and all phases of LA function improved (p=<0.01).
Patients with AF duration < 3 months had lower NT-proANP compared to patients with AF duration from 6 to 12 months (p = 0.005).
Higher NT-proANP concentration before ECV was associated with lower LA reservoir function during the first day after SR restoration (R=-0.456, p=0.005), whereas higher NT-proBNP concentration after 1 month in SR was significantly related to lower LA reservoir function (R=-0.429, p=0.047).
Conclusions.
LA indexed volume, all phases of LA function, and NT-proBNP levels improved significantly following 1 month of SR restoration.
Preliminary results suggest that higher baseline NT-proANP levels and higher NT-proBNP for patients with maintained SR for 1 month are related to lower LA reservoir function.
The longer duration of persistent AF is associated with higher NT-proANP concentration.
American Psychological Association (APA)
Karaliute, Rasa& Jureviciute, Justina& Jurgaityte, Julija& Stanaitiene, Giedre& Mizariene, Vaida& Kazakevicius, Tomas…[et al.]. 2019. Relationship of Natriuretic Peptides with Left Atrial Structure and Function within 1 Month after Electrical Cardioversion in Patients with Persistent Atrial Fibrillation. BioMed Research International،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1127490
Modern Language Association (MLA)
Karaliute, Rasa…[et al.]. Relationship of Natriuretic Peptides with Left Atrial Structure and Function within 1 Month after Electrical Cardioversion in Patients with Persistent Atrial Fibrillation. BioMed Research International No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1127490
American Medical Association (AMA)
Karaliute, Rasa& Jureviciute, Justina& Jurgaityte, Julija& Stanaitiene, Giedre& Mizariene, Vaida& Kazakevicius, Tomas…[et al.]. Relationship of Natriuretic Peptides with Left Atrial Structure and Function within 1 Month after Electrical Cardioversion in Patients with Persistent Atrial Fibrillation. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1127490
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127490
