Research Progress on Regulatory B Cells in Systemic Lupus Erythematosus
Joint Authors
Wang, Tao
Mei, Yongjun
Li, Zhijun
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Systemic lupus erythematosus (SLE) is a chronic, systemic, autoimmune inflammatory disease characterized by the production of numerous autoantibodies and cytokines, as well as multiple organ damage.
Specific B cell subsets negatively regulate immune responses and have been termed regulatory B cells (Bregs).
Bregs are characterized by the production of the immunoregulatory cytokines interleukin (IL)-10, IL-35, and transforming growth factor (TGF)-β.
Bregs suppress other immune cells through the secretion of these immunosuppressive cytokines and have thus been studied extensively for their potential role in the treatment of various autoimmune diseases.
The progress of the research on Bregs and SLE in recent years is reviewed in this paper.
American Psychological Association (APA)
Wang, Tao& Mei, Yongjun& Li, Zhijun. 2019. Research Progress on Regulatory B Cells in Systemic Lupus Erythematosus. BioMed Research International،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1127633
Modern Language Association (MLA)
Wang, Tao…[et al.]. Research Progress on Regulatory B Cells in Systemic Lupus Erythematosus. BioMed Research International No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1127633
American Medical Association (AMA)
Wang, Tao& Mei, Yongjun& Li, Zhijun. Research Progress on Regulatory B Cells in Systemic Lupus Erythematosus. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1127633
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127633