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High Bone Mineral Density of the Lumbar Spine Is Positively Associated with Breast Cancer
Joint Authors
Sousa, Ana Luiza Lima
Gonçalves, Larissa V.
Martins, Karine A.
Freitas-Junior, Ruffo
Godinho-Mota, Jordana Carolina Marques
Schincaglia, Raquel Machado
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-23
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
The objective of this study was to verify possible associations between bone mineral density (BMD) and breast cancer in recently diagnosed women in the Brazilian Mid-west region, considering the menopausal status of patients.
Methods.
A case-control study was conducted with 142 cases of breast cancer and 234 controls matched by for age, body mass index (BMI), and menopausal status (pre- and postmenopause), performed in a university hospital in the Brazilian Mid-west.
Lumbar spine (L1–L4), femoral neck, and total femur BMD were measured by the dual-energy X-ray absorptiometry (DXA) method.
For association, a logistic regression analysis was used.
Results.
Women in the highest lumbar spine BMD quartile presented had a higher chance of developing breast cancer (OR = 2.31; 1.02–5.25; p = 0.045), after adjusting for the confounding variables.
Nonetheless, there were no statistically significant differences in the association between pre- and postmenopause in that quartile and breast cancer.
Conclusions.
High lumbar spine BMD was positively associated with breast cancer in the total sample.
In evaluating the BMD of the femoral neck and total femur, such an association was not observed.
American Psychological Association (APA)
Gonçalves, Larissa V.& Martins, Karine A.& Godinho-Mota, Jordana Carolina Marques& Schincaglia, Raquel Machado& Sousa, Ana Luiza Lima& Freitas-Junior, Ruffo. 2019. High Bone Mineral Density of the Lumbar Spine Is Positively Associated with Breast Cancer. BioMed Research International،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1127651
Modern Language Association (MLA)
Gonçalves, Larissa V.…[et al.]. High Bone Mineral Density of the Lumbar Spine Is Positively Associated with Breast Cancer. BioMed Research International No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1127651
American Medical Association (AMA)
Gonçalves, Larissa V.& Martins, Karine A.& Godinho-Mota, Jordana Carolina Marques& Schincaglia, Raquel Machado& Sousa, Ana Luiza Lima& Freitas-Junior, Ruffo. High Bone Mineral Density of the Lumbar Spine Is Positively Associated with Breast Cancer. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1127651
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127651