Heterogeneity Signs on Noncontrast Computed Tomography Predict Hematoma Expansion after Intracerebral Hemorrhage: A Meta-Analysis
Joint Authors
Wang, Junyu
Hou, Lijun
Xue, Qiang
Zhang, Danfeng
Chen, Jigang
Du, Bingying
Li, Ya
Chen, Tao
Jiang, Ying
Dong, Yan
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background and Purpose.
Hematoma expansion (HE) is related to clinical deterioration after intracerebral hemorrhage (ICH) and noncontrast computed tomography (NCCT) signs are indicated as predictors for HE but with inconsistent conclusions.
We aim to clarify the correlations of NCCT heterogeneity signs with HE by meta-analysis of related studies.
Methods.
PubMed, Embase, and Cochrane library were searched for eligible studies exploring the relationships between NCCT heterogeneity signs (hypodensity, mixed density, swirl sign, blend sign, and black hole sign) and HE.
Poor outcome and mortality were considered as secondary outcomes.
Odds ratio (OR) and its 95% confidence intervals (CIs) were selected as the effect size and combined using random effects model.
Results.
Fourteen studies were included, involving 3240 participants and 435 HEs.
The summary results suggested statistically significant correlations of heterogeneity signs with HE (OR, 5.17; 95% CI, 3.72–7.19, P<0.001), poor outcome (OR, 3.60; 95% CI, 1.98–6.54, P<0.001), and mortality (OR, 4.64; 95%, 2.96–7.27, P<0.001).
Conclusions.
Our findings suggested that hematoma heterogeneity signs on NCCT were positively associated with the increased risk of HE, poor outcome, and mortality rate in ICH.
American Psychological Association (APA)
Zhang, Danfeng& Chen, Jigang& Xue, Qiang& Du, Bingying& Li, Ya& Chen, Tao…[et al.]. 2018. Heterogeneity Signs on Noncontrast Computed Tomography Predict Hematoma Expansion after Intracerebral Hemorrhage: A Meta-Analysis. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1127661
Modern Language Association (MLA)
Zhang, Danfeng…[et al.]. Heterogeneity Signs on Noncontrast Computed Tomography Predict Hematoma Expansion after Intracerebral Hemorrhage: A Meta-Analysis. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1127661
American Medical Association (AMA)
Zhang, Danfeng& Chen, Jigang& Xue, Qiang& Du, Bingying& Li, Ya& Chen, Tao…[et al.]. Heterogeneity Signs on Noncontrast Computed Tomography Predict Hematoma Expansion after Intracerebral Hemorrhage: A Meta-Analysis. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1127661
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127661