Effects of Selenium and Melatonin on Ocular Ischemic Syndrome
Author
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-06
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To determine the effects of selenium, melatonin, and selenium + melatonin administered for one month on anterior chamber (AC) malondialdehyde (MDA) and AC glutathione (GSH) levels in patients with ocular ischemic syndrome.
Materials and Methods.
Thirty-five patients were included in the study.
Study groups were formed as follows: (1) control group, (2) ischemia group, (3) selenium + ischemia group, (4) melatonin + ischemia group, and (5) selenium + melatonin + ischemia group.
AC samples were obtained.
MDA and GSH levels in AC samples were evaluated.
Results.
MDA levels were significantly increased in ischemia groups.
Selenium and melatonin supplementation resulted in reduction of MDA levels and significant increase in GSH values.
Discussion.
Increased lipid peroxidation associated with ischemia of the anterior segment has been prevented by selenium and melatonin supplementation.
This trial is registered with ClinicalTrials.gov NCT04005222.
American Psychological Association (APA)
Telek, Hande Hüsniye. 2019. Effects of Selenium and Melatonin on Ocular Ischemic Syndrome. BioMed Research International،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1127707
Modern Language Association (MLA)
Telek, Hande Hüsniye. Effects of Selenium and Melatonin on Ocular Ischemic Syndrome. BioMed Research International No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1127707
American Medical Association (AMA)
Telek, Hande Hüsniye. Effects of Selenium and Melatonin on Ocular Ischemic Syndrome. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1127707
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127707