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The Significance of Scalp Involvement in Pemphigus: A Literature Review
Joint Authors
Rudnicka, Lidia
Sar-Pomian, Marta
Olszewska, Malgorzata
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Scalp is a unique location for pemphigus because of the abundance of desmogleins localized in hair follicles.
Scalp involvement is observed in up to 60% of patients in the course of pemphigus.
The lesions may occasionally lead to alopecia.
Unforced removal of anagen hairs in a pull test is a sign of high disease activity.
Direct immunofluorescence of plucked hair bulbs is considered a reliable diagnostic method in patients with pemphigus.
Follicular acantholysis is a characteristic histopathological feature of pemphigus lesions localized on the scalp.
Trichoscopy may serve as a supplementary method in the diagnosis of pemphigus.
This review summarizes the most recent data concerning scalp involvement in pemphigus vulgaris and pemphigus foliaceus.
A systematic literature search was conducted in three medical databases: PubMed, Embase, and Web of Science.
The analysis included literature data about desmoglein distribution in hair follicles, as well as information about clinical manifestations, histopathology, immunopathology, and trichoscopy of scalp lesions in pemphigus and their response to treatment.
American Psychological Association (APA)
Sar-Pomian, Marta& Rudnicka, Lidia& Olszewska, Malgorzata. 2018. The Significance of Scalp Involvement in Pemphigus: A Literature Review. BioMed Research International،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1127735
Modern Language Association (MLA)
Sar-Pomian, Marta…[et al.]. The Significance of Scalp Involvement in Pemphigus: A Literature Review. BioMed Research International No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1127735
American Medical Association (AMA)
Sar-Pomian, Marta& Rudnicka, Lidia& Olszewska, Malgorzata. The Significance of Scalp Involvement in Pemphigus: A Literature Review. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1127735
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127735