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Relevance of Topographic Parameters on the Adhesion and Proliferation of Human Gingival Fibroblasts and Oral Bacterial Strains
Joint Authors
Anitua, Eduardo
Pacha-Olivenza, Miguel Ángel
González-Martín, M. Luisa
Tejero, Ricardo
Fernández-Calderón, María Coronada
Troya, María
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-10
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Dental implantology allows replacement of failing teeth providing the patient with a general improvement of health.
Unfortunately not all reconstructions succeed, as a consequence of the development of infections of bacterial origin on the implant surface.
Surface topography is known to modulate a differential response to bacterial and mammalian cells but topographical measurements are often limited to vertical parameters.
In this work we have extended the topographical measurements also to lateral and hybrid parameters of the five most representative implant and prosthetic component surfaces and correlated the results with bacterial and mammalian cell adhesion and proliferation outcomes.
Primary human oral gingival fibroblast (gum cells) and the bacterial strains: Streptococcus mutans, Streptococcus sanguinis and Aggregatibacter actinomycetemcomitans, implicated in infectious processes in the oral/implant environment were employed in the presence or absence of human saliva.
The results confirm that even though not all the measured surface is available for bacteria to adhere, the overall race for the surface between cells and bacteria is more favourable to the smoother surfaces (nitrided, as machined or lightly acid etched) than to the rougher ones (strong acid etched or sandblasted/acid etched).
American Psychological Association (APA)
Pacha-Olivenza, Miguel Ángel& Tejero, Ricardo& Fernández-Calderón, María Coronada& Anitua, Eduardo& Troya, María& González-Martín, M. Luisa. 2019. Relevance of Topographic Parameters on the Adhesion and Proliferation of Human Gingival Fibroblasts and Oral Bacterial Strains. BioMed Research International،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1127915
Modern Language Association (MLA)
Pacha-Olivenza, Miguel Ángel…[et al.]. Relevance of Topographic Parameters on the Adhesion and Proliferation of Human Gingival Fibroblasts and Oral Bacterial Strains. BioMed Research International No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1127915
American Medical Association (AMA)
Pacha-Olivenza, Miguel Ángel& Tejero, Ricardo& Fernández-Calderón, María Coronada& Anitua, Eduardo& Troya, María& González-Martín, M. Luisa. Relevance of Topographic Parameters on the Adhesion and Proliferation of Human Gingival Fibroblasts and Oral Bacterial Strains. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1127915
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127915