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Gut Microbiota-Derived Mediators as Potential Markers in Nonalcoholic Fatty Liver Disease
Joint Authors
Aragonès, Gemma
González-García, Sergio
Auguet, Teresa
Aguilar, Carmen
Richart, Cristóbal
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-02
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Nonalcoholic fatty liver disease (NAFLD) is a common, multifactorial, and poorly understood liver disease whose incidence is globally rising.
During the past decade, several lines of evidence suggest that dysbiosis of intestinal microbiome represents an important factor contributing to NAFLD occurrence and its progression into NASH.
The mechanisms that associate dysbiosis with NAFLD include changes in microbiota-derived mediators, deregulation of the gut endothelial barrier, translocation of mediators of dysbiosis, and hepatic inflammation.
Changes in short chain fatty acids, bile acids, bacterial components, choline, and ethanol are the result of altered intestinal microbiota.
We perform a narrative review of the previously published evidence and discuss the use of gut microbiota-derived mediators as potential markers in NAFLD.
American Psychological Association (APA)
Aragonès, Gemma& González-García, Sergio& Aguilar, Carmen& Richart, Cristóbal& Auguet, Teresa. 2019. Gut Microbiota-Derived Mediators as Potential Markers in Nonalcoholic Fatty Liver Disease. BioMed Research International،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1127932
Modern Language Association (MLA)
Aragonès, Gemma…[et al.]. Gut Microbiota-Derived Mediators as Potential Markers in Nonalcoholic Fatty Liver Disease. BioMed Research International No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1127932
American Medical Association (AMA)
Aragonès, Gemma& González-García, Sergio& Aguilar, Carmen& Richart, Cristóbal& Auguet, Teresa. Gut Microbiota-Derived Mediators as Potential Markers in Nonalcoholic Fatty Liver Disease. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1127932
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127932