Time Course of Cerebrovascular Reactivity in Patients Treated for Unruptured Intracranial Aneurysms: A One-Year Transcranial Doppler and Acetazolamide Follow-Up Study
Joint Authors
Bøthun, Marianne Lundervik
Haaland, Øystein Ariansen
Logallo, Nicola
Svendsen, Frode
Thomassen, Lars
Helland, Christian A.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-26
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
Cerebrovascular reactivity (CVR) is often impaired in the early phase after aneurysmal subarachnoid hemorrhage.
There is, however, little knowledge about the time course of CVR in patients treated for unruptured intracranial aneurysms (UIA).
Methods.
CVR, assessed by transcranial Doppler and acetazolamide test, was examined within the first postoperative week after treatment for UIA and reexamined one year later.
Results.
Of 37 patients initially assessed, 34 were reexamined after one year.
Bilaterally, baseline and acetazolamide-induced blood flow velocities were higher in the postoperative week compared with one year later (p<0.001).
CVR on the ipsilateral side of treatment was lower in the initial examination compared with follow-up (58.9% versus 66.1%, p=0.04).
There was no difference in CVR over time on the contralateral side (63.4% versus 65.0%, p=0.65).
When mean values of right and left sides were considered there was no difference in CVR between exams.
Larger aneurysm size was associated with increased change in CVR (p=0.04), and treatment with clipping was associated with 13.8%-point increased change in CVR compared with coiling (p=0.03).
Conclusion.
Patients with UIA may have a temporary reduction in CVR on the ipsilateral side after aneurysm treatment.
The change in CVR appears more pronounced for larger-sized aneurysms and in patients treated with clipping.
We recommend that ipsilateral and contralateral CVR should be assessed separately, as mean values can conceal side-differences.
American Psychological Association (APA)
Bøthun, Marianne Lundervik& Haaland, Øystein Ariansen& Logallo, Nicola& Svendsen, Frode& Thomassen, Lars& Helland, Christian A.. 2018. Time Course of Cerebrovascular Reactivity in Patients Treated for Unruptured Intracranial Aneurysms: A One-Year Transcranial Doppler and Acetazolamide Follow-Up Study. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1127958
Modern Language Association (MLA)
Bøthun, Marianne Lundervik…[et al.]. Time Course of Cerebrovascular Reactivity in Patients Treated for Unruptured Intracranial Aneurysms: A One-Year Transcranial Doppler and Acetazolamide Follow-Up Study. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1127958
American Medical Association (AMA)
Bøthun, Marianne Lundervik& Haaland, Øystein Ariansen& Logallo, Nicola& Svendsen, Frode& Thomassen, Lars& Helland, Christian A.. Time Course of Cerebrovascular Reactivity in Patients Treated for Unruptured Intracranial Aneurysms: A One-Year Transcranial Doppler and Acetazolamide Follow-Up Study. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1127958
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127958