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Microbiota Composition in Upper Respiratory Tracts of Healthy Children in Shenzhen, China, Differed with Respiratory Sites and Ages
Joint Authors
Zhou, Qian
Dai, Wenkui
Zheng, Yuejie
Wang, Heping
Feng, Xin
Wang, Hongmei
Yang, Yonghong
Li, Shuaicheng
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The upper respiratory tract (URT) is home to various microbial commensals, which function as competitors to pathogens and help train the immune system.
However, few studies have reported the normal microbiota carriage in the URT of healthy Chinese children.
In this study, we performed a 16S rDNA gene sequencing analysis of 83 anterior nares (ANs), 60 nasopharynx (NP), and 97 oropharynx (OP) samples from 98 healthy children in Shenzhen, China (≤12 years of age).
The microbiota in ANs and NP is the same at different ages and typical species in these sites include Moraxella, Staphylococcus, Corynebacterium, Streptococcus, and Dolosigranulum.
By contrast, the OP is primarily colonized by Streptococcus, Prevotella, Neisseria, Veillonella, Rothia, Leptotrichia, and Haemophilus.
Streptococcus and Rothia keep low abundance in OP microbiota of children ≤1 year old, whereas Prevotella, Neisseria, Haemophilus, and Leptotrichia amass significantly in individuals >1 year old.
This work furnishes an important reference for understanding microbial dysbiosis in the URT of Chinese paediatric patients.
American Psychological Association (APA)
Wang, Heping& Dai, Wenkui& Feng, Xin& Zhou, Qian& Wang, Hongmei& Yang, Yonghong…[et al.]. 2018. Microbiota Composition in Upper Respiratory Tracts of Healthy Children in Shenzhen, China, Differed with Respiratory Sites and Ages. BioMed Research International،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1127977
Modern Language Association (MLA)
Wang, Heping…[et al.]. Microbiota Composition in Upper Respiratory Tracts of Healthy Children in Shenzhen, China, Differed with Respiratory Sites and Ages. BioMed Research International No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1127977
American Medical Association (AMA)
Wang, Heping& Dai, Wenkui& Feng, Xin& Zhou, Qian& Wang, Hongmei& Yang, Yonghong…[et al.]. Microbiota Composition in Upper Respiratory Tracts of Healthy Children in Shenzhen, China, Differed with Respiratory Sites and Ages. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1127977
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127977