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Prognostic Value and Therapeutic Perspectives of Coronary CT Angiography: A Literature Review
Joint Authors
Guaricci, Andrea Igoren
Patrizia, Carità
Moscogiuri, Giuseppe
Carrabba, Nazario
Pontone, G.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-16
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Coronary stenosis severity is both a powerful and a still debated predictor of prognosis in coronary artery disease.
Coronary computed tomographic angiography (CCTA) has emerged as a noninvasive technique that enables anatomic visualization of coronary artery disease (CAD).
CCTA with newer applications, plaque characterization and physiologic/functional evaluation, allows a comprehensive diagnostic and prognostic assessment of otherwise low-intermediate subjects for primary prevention.
CCTA measures the overall plaque burden, differentiates plaque subtypes, and identifies high-risk plaque with good reproducibility.
Research in this field may also advance towards an era of personalized risk prediction and individualized medical therapy.
It has been demonstrated that statins may delay plaque progression and change some plaque features.
The potential effects on plaque modifications induced by other medical therapies have also been investigated.
Although it is not currently possible to recommend routinely serial scans to monitor the therapeutic efficacy of medical interventions, the plaque modulation, as a part of risk modification, appears a feasible strategy.
In this review we summarize the current evidence regarding vulnerable plaque and effects of lipid lowering therapy on morphological features of CAD.
We also discuss the potential ability of CCTA to characterize coronary atherosclerosis, stratify prognosis of asymptomatic subjects, and guide medical therapy.
American Psychological Association (APA)
Patrizia, Carità& Guaricci, Andrea Igoren& Moscogiuri, Giuseppe& Carrabba, Nazario& Pontone, G.. 2018. Prognostic Value and Therapeutic Perspectives of Coronary CT Angiography: A Literature Review. BioMed Research International،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1127979
Modern Language Association (MLA)
Patrizia, Carità…[et al.]. Prognostic Value and Therapeutic Perspectives of Coronary CT Angiography: A Literature Review. BioMed Research International No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1127979
American Medical Association (AMA)
Patrizia, Carità& Guaricci, Andrea Igoren& Moscogiuri, Giuseppe& Carrabba, Nazario& Pontone, G.. Prognostic Value and Therapeutic Perspectives of Coronary CT Angiography: A Literature Review. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1127979
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127979