Effectiveness and Safety of Peritoneal Dialysis Treatment in Patients with Refractory Congestive Heart Failure due to Chronic Cardiorenal Syndrome
Joint Authors
Jiang, Chunming
Shao, Qiuyuan
Jin, Bo
Gong, Rujun
Xu, Biao
Zhao, Min
Xie, Jun
Xia, Yangyang
Liu, Jing
Zhang, Qingyan
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-17
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Aims.
To evaluate the effectiveness and safety of peritoneal dialysis (PD) in treating refractory congestive heart failure (RCHF) with cardiorenal syndrome (CRS).
Methods.
A total of 36 patients with RCHF were divided into type 2 CRS group (group A) and non-type 2 CRS group (group B) according to the patients’ clinical presentations and the ratio of serum urea to creatinine and urinary analyses in this prospective study.
All patients were followed up till death or discontinuation of PD.
Data were collected for analysis, including patient survival time on PD, technique failure, changes of heart function, and complications associated with PD treatment and hospitalization.
Results.
There were 27 deaths and 9 patients quitting PD program after a follow-up for 73 months with an average PD time of 22.8±18.2 months.
A significant longer PD time was found in group B as compared with that in group A (29.0±19.4 versus 13.1±10.6 months, p=0.003).
Kaplan–Meier curves showed a higher survival probability in group B than that in group A (p<0.001).
Multivariate regression demonstrated that type 2 CRS was an independent risk factor for short survival time on PD.
The benefit of PD on the improvement of survival and LVEF was limited to group B patients, but absent from group A patients.
The impairment of exercise tolerance indicated by NYHA classification was markedly improved by PD for both groups.
The technique survival was high, and the hospital readmission was evidently decreased for both group A and group B patients.
Conclusions.
Our data suggest that PD is a safe and feasible palliative treatment for RCHF with type 2 CRS, though the long-term survival could not be expected for patients with the type 2 CRS.
Registration ID Number is ChiCTR1800015910.
American Psychological Association (APA)
Shao, Qiuyuan& Xia, Yangyang& Zhao, Min& Liu, Jing& Zhang, Qingyan& Jin, Bo…[et al.]. 2018. Effectiveness and Safety of Peritoneal Dialysis Treatment in Patients with Refractory Congestive Heart Failure due to Chronic Cardiorenal Syndrome. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1127981
Modern Language Association (MLA)
Shao, Qiuyuan…[et al.]. Effectiveness and Safety of Peritoneal Dialysis Treatment in Patients with Refractory Congestive Heart Failure due to Chronic Cardiorenal Syndrome. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1127981
American Medical Association (AMA)
Shao, Qiuyuan& Xia, Yangyang& Zhao, Min& Liu, Jing& Zhang, Qingyan& Jin, Bo…[et al.]. Effectiveness and Safety of Peritoneal Dialysis Treatment in Patients with Refractory Congestive Heart Failure due to Chronic Cardiorenal Syndrome. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1127981
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1127981