Acute and Long-Term Hemodynamic Effects of MitraClip Implantation on a Preexisting Secondary Right Heart Failure
Joint Authors
Blankenberg, Stefan
Schäfer, Ulrich
Lubos, Edith
Schillinger, Wolfgang
Hünlich, M.
Beuthner, B. E.
Puls, M.
Bleckmann, A.
Beißbarth, T.
Tichelbäcker, T.
Rudolph, V.
Baldus, S.
Treede, H.
Von Bardeleben, R. S.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-14
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Positive results of MitraClip in terms of improvement in clinical and left ventricular parameters have been described in detail.
However, long-term effects on secondary pulmonary hypertension were not investigated in a larger patient cohort to date.
70 patients with severe mitral regurgitation, additional pulmonary hypertension, and right heart failure as a result of left heart disease were treated in the heart centers Hamburg and Göttingen.
Immediately after successful MitraClip implantation, a reduction of the RVOT diameter from 3.52 cm to 3.44 cm was observed reaching a statistically significant value of 3.39 cm after 12 months.
In contrast, there was a significant reduction in the velocity of the tricuspid regurgitation (TR) from 4.17 m/s to 3.11 m/s, the gradient of the TR from 48.5 mmHg to 39.3 mmHg, and the systolic pulmonary artery pressure (PAPsyst) from 58.6 mmHg to 50.0 mmHg.
This decline continued in the following months (Vmax TR 3.09 m/s, peak TR 38.6 mmHg, and PAPsyst 47.4 mmHg).
The tricuspid annular plane systolic excursion (TAPSE) increased from 16.5 mm to 18.9 mm after 12 months.
MitraClip implantation improves pulmonary artery pressure, tricuspid regurgitation, and TAPSE after 12 months.
At the same time, there is a decrease in the RVOT diameter without significant changes in other right ventricular and right atrial dimensions.
American Psychological Association (APA)
Hünlich, M.& Lubos, Edith& Beuthner, B. E.& Puls, M.& Bleckmann, A.& Beißbarth, T.…[et al.]. 2018. Acute and Long-Term Hemodynamic Effects of MitraClip Implantation on a Preexisting Secondary Right Heart Failure. BioMed Research International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1128109
Modern Language Association (MLA)
Hünlich, M.…[et al.]. Acute and Long-Term Hemodynamic Effects of MitraClip Implantation on a Preexisting Secondary Right Heart Failure. BioMed Research International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1128109
American Medical Association (AMA)
Hünlich, M.& Lubos, Edith& Beuthner, B. E.& Puls, M.& Bleckmann, A.& Beißbarth, T.…[et al.]. Acute and Long-Term Hemodynamic Effects of MitraClip Implantation on a Preexisting Secondary Right Heart Failure. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1128109
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128109