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Association of Antibiotic Resistance, Cell Adherence, and Biofilm Production with the Endemicity of Nosocomial Klebsiella pneumoniae
Joint Authors
Rodriguez-Noriega, Eduardo
Santos-Preciado, José Ignacio
Alcántar-Curiel, María Dolores
Ledezma-Escalante, Carmen Alejandra
Jarillo-Quijada, Ma Dolores
Gayosso-Vázquez, Catalina
Morfín-Otero, Rayo
Cedillo-Ramírez, María Lilia
Girón, Jorge A.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-23
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Klebsiella pneumoniae is a leading cause of multiple nosocomial infections, some of which are associated with high mortality.
The increasing prevalence of antibiotic-resistant strains highlights their clinical importance and how complicated managing treatment can be.
In this study, we investigated antimicrobial resistance, cell adherence, and biofilm production of nosocomial K.
pneumoniae strains isolated from surveillance studies in a Mexican tertiary hospital and evaluated the potential association of these phenotypes with endemicity.
The great majority of the clones exhibited adhesion to cultured epithelial cells and were strong biofilm producers.
A direct relationship between adhesion phenotypes, biofilm production, and endemicity was not always apparent.
Biofilm formation and production of ESBL did not appear to be directly associated.
Notably, all the endemic strains were multidrug-resistant.
This study emphasizes that while endemic strains possess various virulence-associated properties, antimicrobial resistance appears to be a determining factor of their endemicity.
American Psychological Association (APA)
Alcántar-Curiel, María Dolores& Ledezma-Escalante, Carmen Alejandra& Jarillo-Quijada, Ma Dolores& Gayosso-Vázquez, Catalina& Morfín-Otero, Rayo& Rodriguez-Noriega, Eduardo…[et al.]. 2018. Association of Antibiotic Resistance, Cell Adherence, and Biofilm Production with the Endemicity of Nosocomial Klebsiella pneumoniae. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1128218
Modern Language Association (MLA)
Alcántar-Curiel, María Dolores…[et al.]. Association of Antibiotic Resistance, Cell Adherence, and Biofilm Production with the Endemicity of Nosocomial Klebsiella pneumoniae. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1128218
American Medical Association (AMA)
Alcántar-Curiel, María Dolores& Ledezma-Escalante, Carmen Alejandra& Jarillo-Quijada, Ma Dolores& Gayosso-Vázquez, Catalina& Morfín-Otero, Rayo& Rodriguez-Noriega, Eduardo…[et al.]. Association of Antibiotic Resistance, Cell Adherence, and Biofilm Production with the Endemicity of Nosocomial Klebsiella pneumoniae. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1128218
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128218