Anterior Capsule of the Lens: Comparison of Morphological Properties and Apoptosis Induction following FLACS and Standard Phacoemulsification Surgery
Joint Authors
Cavallini, Gian Maria
Pisciotta, Alessandra
De Maria, Michele
Verdina, Tommaso
Fornasari, Elisa
De Pol, Anto
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
Comparative evaluation of morphological features of anterior capsules and apoptosis induction in epithelial cells after femtosecond laser-assisted cataract surgery (FLACS) and standard phacoemulsification surgery.
Methods.
Group 1: 30 FLACS anterior capsulotomies and Group 2: 30 manual anterior continuous curvilinear capsulorhexes.
All patients were operated on by the same experienced surgeon.
Morphological features of the anterior capsules and apoptosis induction in epithelial cells were evaluated.
Results.
All patients revealed a significant mean best-corrected visual acuity (BCVA) improvement 3 months after surgery, and no major intraoperative nor postoperative complications occurred.
The capsular epithelium appeared to be preserved in both groups.
Scanning electron microscopy analysis revealed irregular saw-tooth shaped edges in capsules from Group 1 whereas capsules from Group 2 showed regular and smooth edges.
A statistically significant higher expression of the downstream apoptotic effector cleaved caspase 3 was observed in Group 1.
Conclusions.
The saw-tooth appearance was likely due to the progressive sequence of laser pulses on the capsule.
The low energy/high frequency properties of the laser pulse, combined with an overlapped pulse pattern, resulted in highly continuous morphology of capsule edges.
The higher apoptosis induction in FLACS group might be due to photodisruption-dependent plasma generation and formation of cavitation bubbles.
American Psychological Association (APA)
Pisciotta, Alessandra& De Maria, Michele& Verdina, Tommaso& Fornasari, Elisa& De Pol, Anto& Cavallini, Gian Maria. 2018. Anterior Capsule of the Lens: Comparison of Morphological Properties and Apoptosis Induction following FLACS and Standard Phacoemulsification Surgery. BioMed Research International،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1128350
Modern Language Association (MLA)
Pisciotta, Alessandra…[et al.]. Anterior Capsule of the Lens: Comparison of Morphological Properties and Apoptosis Induction following FLACS and Standard Phacoemulsification Surgery. BioMed Research International No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1128350
American Medical Association (AMA)
Pisciotta, Alessandra& De Maria, Michele& Verdina, Tommaso& Fornasari, Elisa& De Pol, Anto& Cavallini, Gian Maria. Anterior Capsule of the Lens: Comparison of Morphological Properties and Apoptosis Induction following FLACS and Standard Phacoemulsification Surgery. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1128350
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128350