Evaluation of Antibacterial Effect against Porphyromonas gingivalis and Biocompatibility of Essential Oil Extracted from the Gum of Pistacia atlantica Kurdica
Joint Authors
Azeez, Shokhan H.
Gaphor, Shanaz M.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-29
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Objective.
This study investigates the antibacterial effect of essential oil extracted from the gum of Pistacia atlantica Kurdica against Porphyromonas gingivalis and histological evaluation of an experimental gel of the extract in wound healing in the back subcutaneous tissue of Wistar rats.
Methods.
Clinical strains of bacteria obtained from subgingival plaque samples of individuals having periodontitis, isolation, and confirmation were done by conventional microbiological tests and molecular technique.
Essential oil was extracted by using hydrodistillation method; antibacterial activity has been determined by two fold serial dilution method.
Histological evaluation conducted on fifteen Wistar rats.
Incisions were made on the dorsal surface of each animal for implanting of 3 polysilicone tubes (empty, tetracycline gel, and the experimental gel).
After 1, 4, and 8 weeks, the animals were euthanized and the specimens were prepared histologically.
Result.
The extract demonstrated antimicrobial effect and significant wound healing in the different study durations particularly our product showed progression in epidermal wound healing and decrease in cellularity and scoring of inflammatory cells.
Conclusion.
The extract was able to pose inhibitory and bactericidal activity against P.
gingivalis and the experimental gel was able to have a good wound healing that enable it to be considered as a compatible material.
American Psychological Association (APA)
Azeez, Shokhan H.& Gaphor, Shanaz M.. 2019. Evaluation of Antibacterial Effect against Porphyromonas gingivalis and Biocompatibility of Essential Oil Extracted from the Gum of Pistacia atlantica Kurdica. BioMed Research International،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1128373
Modern Language Association (MLA)
Azeez, Shokhan H.& Gaphor, Shanaz M.. Evaluation of Antibacterial Effect against Porphyromonas gingivalis and Biocompatibility of Essential Oil Extracted from the Gum of Pistacia atlantica Kurdica. BioMed Research International No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1128373
American Medical Association (AMA)
Azeez, Shokhan H.& Gaphor, Shanaz M.. Evaluation of Antibacterial Effect against Porphyromonas gingivalis and Biocompatibility of Essential Oil Extracted from the Gum of Pistacia atlantica Kurdica. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1128373
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128373