Drosophila as a Model System to Study Cell Signaling in Organ Regeneration
Joint Authors
Baonza, Antonio
Ahmed-de-Prado, Sara
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-19
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Regeneration is a fascinating phenomenon that allows organisms to replace or repair damaged organs or tissues.
This ability occurs to varying extents among metazoans.
The rebuilding of the damaged structure depends on regenerative proliferation that must be accompanied by proper cell fate respecification and patterning.
These cellular processes are regulated by the action of different signaling pathways that are activated in response to the damage.
The imaginal discs of Drosophila melanogaster have the ability to regenerate and have been extensively used as a model system to study regeneration.
Drosophila provides an opportunity to use powerful genetic tools to address fundamental problems about the genetic mechanisms involved in organ regeneration.
Different studies in Drosophila have helped to elucidate the genes and signaling pathways that initiate regeneration, promote regenerative growth, and induce cell fate respecification.
Here we review the signaling networks involved in regulating the variety of cellular responses that are required for discs regeneration.
American Psychological Association (APA)
Ahmed-de-Prado, Sara& Baonza, Antonio. 2018. Drosophila as a Model System to Study Cell Signaling in Organ Regeneration. BioMed Research International،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1128424
Modern Language Association (MLA)
Ahmed-de-Prado, Sara& Baonza, Antonio. Drosophila as a Model System to Study Cell Signaling in Organ Regeneration. BioMed Research International No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1128424
American Medical Association (AMA)
Ahmed-de-Prado, Sara& Baonza, Antonio. Drosophila as a Model System to Study Cell Signaling in Organ Regeneration. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1128424
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128424