A New Insight into the Roles of MiRNAs in Metabolic Syndrome
Joint Authors
Zou, Hequn
Huang, Yuxiang
Yan, Yuxiang
Xv, Weicheng
Qian, Ge
Li, Chijian
Li, Yongqiang
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-17
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Metabolic syndrome (MetS), which includes several clinical components such as abdominal obesity, insulin resistance (IR), dyslipidemia, microalbuminuria, hypertension, proinflammatory state, and oxidative stress (OS), has become a global epidemic health issue contributing to a high risk of type 2 diabetes mellitus (T2DM).
In recent years, microRNAs (miRNAs), used as noninvasive biomarkers for diagnosis and therapy, have aroused global interest in complex processes in health and diseases, including MetS and its components.
MiRNAs can exist stably in serum, liver, skeletal muscle (SM), heart muscle, adipose tissue (AT), and βcells, because of their ability to escape the digestion of RNase.
Here we first present an overall review on recent findings of the relationship between miRNAs and several main components of MetS, such as IR, obesity, diabetes, lipid metabolism, hypertension, hyperuricemia, and stress, to illustrate the targeting proteins or relevant pathways that are involved in the progress of MetS and also help us find promising novel diagnostic and therapeutic strategies.
American Psychological Association (APA)
Huang, Yuxiang& Yan, Yuxiang& Xv, Weicheng& Qian, Ge& Li, Chijian& Zou, Hequn…[et al.]. 2018. A New Insight into the Roles of MiRNAs in Metabolic Syndrome. BioMed Research International،Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1128434
Modern Language Association (MLA)
Huang, Yuxiang…[et al.]. A New Insight into the Roles of MiRNAs in Metabolic Syndrome. BioMed Research International No. 2018 (2018), pp.1-15.
https://search.emarefa.net/detail/BIM-1128434
American Medical Association (AMA)
Huang, Yuxiang& Yan, Yuxiang& Xv, Weicheng& Qian, Ge& Li, Chijian& Zou, Hequn…[et al.]. A New Insight into the Roles of MiRNAs in Metabolic Syndrome. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1128434
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128434