Ultrasound Measurements of Fetal Thyroid: Reference Ranges from a Cohort of Low-Risk Pregnant Women
Joint Authors
Souza, Renato T.
Barbosa, R. M.
Andrade, K. C.
Silveira, C.
Almeida, C. M.
Oliveira, P. F
Cecatti, Jose Guilherme
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Adequate thyroid function is essential for normal growth and development of the fetus.
Sonographic recognition of alterations in fetal thyroid dimensions may be the first sign of thyroid dysfunction, permitting early diagnosis and intervention.
The main goal of this study was to build curves with reference values for ultrasound measurements of the fetal thyroid from 14 to 40 weeks of gestation.
Methods.
This is a prospective longitudinal study of 90 Brazilian pregnant women, complementary to a cohort multicentre study named “WHO multicentre study for the development of growth standards from fetal life to childhood: the fetal component.” Pregnant women without any pre-existing conditions that might affect fetal growth received antenatal care from the first trimester until childbirth, undergoing serial ultrasound evaluations of the fetus, including the thyroid.
Longitudinal, anteroposterior, and transverse diameters of both thyroid lobes were measured in the fetus.
Fetal thyroid lobe volume was also estimated.
By quantile regression analysis, reference curves of measurements were fitted according to the gestational age.
Results.
A reference standard of thyroid growth was defined during pregnancy by fitting curves of its measurements.
Reference values for the 10th, 50th, and 90th centiles of fetal thyroid measurements (longitudinal, anteroposterior, transverse diameters, and lobe volume) were defined, from 14 to 40 weeks of gestation.
Conclusion.
We provided a reference curve of optimal thyroid development in a low-risk population that can be used as a standard of comparison to diagnose deviations from the norm.
In addition, we demonstrated an alternative and simplified method for early recognition of thyroid morphological alterations by an individualized technique to evaluate the thyroid lobes.
American Psychological Association (APA)
Barbosa, R. M.& Andrade, K. C.& Silveira, C.& Almeida, C. M.& Souza, Renato T.& Oliveira, P. F…[et al.]. 2019. Ultrasound Measurements of Fetal Thyroid: Reference Ranges from a Cohort of Low-Risk Pregnant Women. BioMed Research International،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1128603
Modern Language Association (MLA)
Barbosa, R. M.…[et al.]. Ultrasound Measurements of Fetal Thyroid: Reference Ranges from a Cohort of Low-Risk Pregnant Women. BioMed Research International No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1128603
American Medical Association (AMA)
Barbosa, R. M.& Andrade, K. C.& Silveira, C.& Almeida, C. M.& Souza, Renato T.& Oliveira, P. F…[et al.]. Ultrasound Measurements of Fetal Thyroid: Reference Ranges from a Cohort of Low-Risk Pregnant Women. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1128603
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128603