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Evaluation of New Film Based on ChitosanGold Nanocomposites on Antibacterial Property and Wound-Healing Efficacy
Joint Authors
Li, Hongru
Qi, Zhiping
Chang, Yuxin
Fu, Chuan
Yang, Xiaoyu
Pan, Su
Wang, Kai
Wang, Haosheng
Source
Advances in Materials Science and Engineering
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-29
Country of Publication
Egypt
No. of Pages
10
Abstract EN
Chitosan (CS) is a natural polymer with applications in wound restorations and coatings for artificial implants.
However, the lack of antimicrobial activity restricts its further application.
Thus, the purpose of this study is to prepare CS/AuNPs film by adding gold nanoparticles (AuNPs) to modify chitosan.
Through transmission electron microscopy, we found that the presence of CS can effectively prevent the agglomeration of nanoparticles.
Furthermore, through the CCK experiment, we found that AuNPs at a certain concentration can improve the adhesion and proliferation of cells, which has also been proved in animal experiments, including gross appearance, histological observations, and immunofluorescence staining.
Such findings support the feasibility of using the film as a promising candidate for tissue engineering of skin in a near future.
American Psychological Association (APA)
Wang, Kai& Wang, Haosheng& Pan, Su& Fu, Chuan& Chang, Yuxin& Li, Hongru…[et al.]. 2020. Evaluation of New Film Based on ChitosanGold Nanocomposites on Antibacterial Property and Wound-Healing Efficacy. Advances in Materials Science and Engineering،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1128771
Modern Language Association (MLA)
Wang, Kai…[et al.]. Evaluation of New Film Based on ChitosanGold Nanocomposites on Antibacterial Property and Wound-Healing Efficacy. Advances in Materials Science and Engineering No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1128771
American Medical Association (AMA)
Wang, Kai& Wang, Haosheng& Pan, Su& Fu, Chuan& Chang, Yuxin& Li, Hongru…[et al.]. Evaluation of New Film Based on ChitosanGold Nanocomposites on Antibacterial Property and Wound-Healing Efficacy. Advances in Materials Science and Engineering. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1128771
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128771