Retrospective Analysis of Intravaginal Brachytherapy in Adjuvant Treatment of Early Endometrial Cancer
Joint Authors
Cisek, Paweł
Kieszko, Dariusz
Kordzińska-Cisek, Izabela
Kutarska, Elżbieta
Grzybowska-Szatkowska, Ludmiła
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-21
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The aim of this study was to determine the role of adjuvant endovaginal brachytherapy HDR (High Dose Rate) or observation, as well as identification of risk factors of tumor recurrence.
The study included 178 women after radical hysterectomy.
All patients belonged to the group of low- and medium-risk stage I FIGO.
Analysis consisted of 3-, 5-, and 10-year OS, DFS, and LRFS in both groups.
Follow-up was more than 6.5 years.
The 5-OS, 5-DFS, and 5-LRFS were 93%, 96%, and 98% in the treated group and 95%, 94%, and 96% in the observed group, respectively.
These differences were not statistically significant.
There was a statistically significant difference in 5-OS in the treated group, between low- and medium-risk subgroups (100% versus 87.55%, p = 0.018 ).
There was a better prognosis among the patients with FIGO IA compared to FIGO IB (5-DFS, 97 versus 86%, p = 0.047 ).
Among the risk factors, there were only statistically significant differences in the 5-OS, between the ages of ≤ 70 years and >70 years.
Use of brachytherapy may affect the reduction in the number of local recurrences at the vaginal stump (6% versus 2%).
This is particularly noticeable in the low-risk subgroup (9% versus 0%).
American Psychological Association (APA)
Cisek, Paweł& Kieszko, Dariusz& Kordzińska-Cisek, Izabela& Kutarska, Elżbieta& Grzybowska-Szatkowska, Ludmiła. 2018. Retrospective Analysis of Intravaginal Brachytherapy in Adjuvant Treatment of Early Endometrial Cancer. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1128788
Modern Language Association (MLA)
Cisek, Paweł…[et al.]. Retrospective Analysis of Intravaginal Brachytherapy in Adjuvant Treatment of Early Endometrial Cancer. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1128788
American Medical Association (AMA)
Cisek, Paweł& Kieszko, Dariusz& Kordzińska-Cisek, Izabela& Kutarska, Elżbieta& Grzybowska-Szatkowska, Ludmiła. Retrospective Analysis of Intravaginal Brachytherapy in Adjuvant Treatment of Early Endometrial Cancer. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1128788
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128788