![](/images/graphics-bg.png)
Snake-Eyes Appearance on MRI Occurs during the Late Stage of Hirayama Disease and Indicates Poor Prognosis
Joint Authors
Shao, Minghao
Lu, Feizhou
Wang, Hongli
Jiang, Jianyuan
Ma, Xiaosheng
Xia, Xinlei
Xu, Haocheng
Zhang, Fan
Nie, Cong
Zhu, Wei
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-13
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
Because Hirayama disease is stereotyped as a self-limited disease in the absence of a definite pathology, we investigated the potential relationship between snake-eyes appearance (SEA) and Hirayama disease to bring a new perspective in the pathological process of Hirayama disease based on relevant radiological and clinical evidence.
Methods.
A total of 30 cases observed SEA were selected from 293 patients with Hirayama disease to constitute the SEA group, and an equal number of cases were randomly selected from the remaining patients to form the non-SEA group.
Cervical magnetic resonance imaging (MRI) was performed and subsequently used to measure the anteroposterior diameter and anterior shifting of the spinal cord.
Additionally, clinical data, such as age, sex, duration of symptoms, symptoms, and signs, were collected and analyzed.
Results.
Of 293 patients, 10.6% appeared with the SEA, which was mainly multisegmental (86.7%), particularly at the C5-6 segment (73.3%), and intense with a well-defined border (70.0%).
The SEA group was an older population (p < 0.0001) with a longer duration (p < 0.0001) and a higher incidence of Hoffmann signs and knee hyperreflexia (p < 0.0001, p = 0.0038, respectively).
The degree of spinal cord atrophy demonstrated a close association with the SEA, as it was significantly worse in the SEA group and SEA segment (p = 0.0008, p < 0.0001, respectively).
The degree of spinal cord atrophy was positively related to both age and duration (p = 0.0095, p = 0.0176, respectively).
Conclusions.
Confirmed as an irreversible lesion and an indication of poor prognosis, SEA appears during the late stage of Hirayama disease and is closely related to pyramidal signs and spinal cord atrophy.
American Psychological Association (APA)
Xu, Haocheng& Shao, Minghao& Zhang, Fan& Nie, Cong& Wang, Hongli& Zhu, Wei…[et al.]. 2019. Snake-Eyes Appearance on MRI Occurs during the Late Stage of Hirayama Disease and Indicates Poor Prognosis. BioMed Research International،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1128866
Modern Language Association (MLA)
Xu, Haocheng…[et al.]. Snake-Eyes Appearance on MRI Occurs during the Late Stage of Hirayama Disease and Indicates Poor Prognosis. BioMed Research International No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1128866
American Medical Association (AMA)
Xu, Haocheng& Shao, Minghao& Zhang, Fan& Nie, Cong& Wang, Hongli& Zhu, Wei…[et al.]. Snake-Eyes Appearance on MRI Occurs during the Late Stage of Hirayama Disease and Indicates Poor Prognosis. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1128866
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128866