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Myeloid Sarcoma That Infiltrated a Preexisting Sebaceous Lymphadenoma in the Parotid Gland: Diagnostic Challenges and Literature Review
Joint Authors
Jo, Sunmi
Shim, Hye-kyung
Kim, Joo Yeon
Bae, Sang Kyun
Kim, Mi Ra
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-22
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Myeloid sarcoma (MS) is a rarely encountered extramedullary localized tumor that is composed of immature myeloid cells.
We reported an extremely rare case of MS with concurrent bone marrow (BM) involvement that invaded into a preexisting sebaceous lymphadenoma in the parotid gland and neck lymph nodes.
Prompted by this case, we also present a literature review of MS invasion into salivary glands.
A 62-year-old man was initially diagnosed with carcinoma that arose in a sebaceous lymphadenoma in the parotid gland, through a total parotidectomy with neck dissection.
After an extensive histopathological review that included immunohistochemistry, a pathologic diagnosis of MS with infiltration into the sebaceous lymphadenoma with concurrent BM involvement was confirmed.
MS is difficult to diagnose accurately; herein, we analyzed the clinical presentations and effectiveness of the various diagnostic methods with a review of the literature.
There are 17 cases, including our case, reported in 13 studies.
Of the cases in which the salivary glands were affected, 10 involved the parotid gland, six involved the submandibular gland, and one involved both.
Isolated invasion of the salivary gland was found in one case of parotid gland invasion and three cases of submandibular gland invasion.
In 13 cases, the salivary glands were affected by various other lesions.
Although there were no incidences of isolated MS, six patients were diagnosed with secondary MS and eight patients with MS with BM involvement, including this case.
The diagnosis of MS is difficult given its rarity, and a high index of suspicion and integrated radiologic and careful histopathologic evaluation are required.
Most cases of MS infiltrating the salivary gland might be indicated by the possibility of BM involvement.
MS with BM involvement predicts poor prognosis and the need for intensive systemic treatment.
American Psychological Association (APA)
Jo, Sunmi& Shim, Hye-kyung& Kim, Joo Yeon& Bae, Sang Kyun& Kim, Mi Ra. 2019. Myeloid Sarcoma That Infiltrated a Preexisting Sebaceous Lymphadenoma in the Parotid Gland: Diagnostic Challenges and Literature Review. BioMed Research International،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1128899
Modern Language Association (MLA)
Jo, Sunmi…[et al.]. Myeloid Sarcoma That Infiltrated a Preexisting Sebaceous Lymphadenoma in the Parotid Gland: Diagnostic Challenges and Literature Review. BioMed Research International No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1128899
American Medical Association (AMA)
Jo, Sunmi& Shim, Hye-kyung& Kim, Joo Yeon& Bae, Sang Kyun& Kim, Mi Ra. Myeloid Sarcoma That Infiltrated a Preexisting Sebaceous Lymphadenoma in the Parotid Gland: Diagnostic Challenges and Literature Review. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1128899
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128899