A Systematic Review of Long Noncoding RNAs in Hepatocellular Carcinoma: Molecular Mechanism and Clinical Implications
Joint Authors
Hu, Xiaoge
Xu, Qiuran
Ni, Chao
Jiang, Jiahong
Huang, Dongsheng
Yang, Liu
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-09
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Hepatocellular carcinoma (HCC) has the second highest mortality rate worldwide among all cancers.
Previous studies have revealed the significant involvement of long noncoding RNAs (lncRNAs) in numerous human cancers including HCC.
Both oncogenic and tumor repressive lncRNAs have been identified and implicated in the complex process of hepatocarcinogenesis.
They can be further explored as prospective diagnostic, prognostic, and therapeutic markers for HCC.
An in-depth understanding of lncRNAs’ mechanism in HCC is therefore required to fully explore their potential role.
In the current review, we will concentrate on the underlying function, molecular mechanisms, and potential clinical implications of lncRNA in HCC.
American Psychological Association (APA)
Hu, Xiaoge& Jiang, Jiahong& Xu, Qiuran& Ni, Chao& Yang, Liu& Huang, Dongsheng. 2018. A Systematic Review of Long Noncoding RNAs in Hepatocellular Carcinoma: Molecular Mechanism and Clinical Implications. BioMed Research International،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1128906
Modern Language Association (MLA)
Hu, Xiaoge…[et al.]. A Systematic Review of Long Noncoding RNAs in Hepatocellular Carcinoma: Molecular Mechanism and Clinical Implications. BioMed Research International No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1128906
American Medical Association (AMA)
Hu, Xiaoge& Jiang, Jiahong& Xu, Qiuran& Ni, Chao& Yang, Liu& Huang, Dongsheng. A Systematic Review of Long Noncoding RNAs in Hepatocellular Carcinoma: Molecular Mechanism and Clinical Implications. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1128906
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1128906