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Impact of Obesity on Long-Term Urinary Incontinence after Radical Prostatectomy: A Meta-Analysis
Joint Authors
Wei, Yong
Wu, Yu-Peng
Lin, Min-Yi
Chen, Shao-Hao
Lin, Yun-Zhi
Li, Xiao-Dong
Zheng, Qing-Shui
Xue, Xue-Yi
Xu, Ning
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Obesity is a known risk factor for prostate cancer progression and may contribute to poor treatment outcomes.
However, little is known concerning the relationship between obesity (body mass index [BMI] ⩾ 30) and the urinary incontinence (UI) of patients after radical prostatectomy (RP).
The goal of this study was to focus on the prevalence and duration of UI after RP with specific attention to the BMI.
Subsequently, trials were identified in a literature search of PubMed, Embase, Cochrane Library, Web of Science, and Google Scholar using appropriate search terms.
All comparative studies reporting BMI, study characteristics, and outcome data including the relationship between BMI and urinary incontinence data were included.
Finally, four studies comprising 6 trials with 2890 participants were included.
The results showed that obesity increased UI risk at 12 months in patients who underwent robotic-assisted laparoscopic radical prostatectomy (RLRP) (odds ratio [OR] 2.43, 95% confidence interval [CI] [1.21, 4.88], P=0.01).
When stratified by the surgical methods, the pooled results showed that obesity increased UI risk at 24 months in patients who underwent RLRP (OR 2.00, 95% CI [1.57, 2.56], P<0.001).
However, in patients who underwent laparoscopic radical prostatectomy (LRP), the pooled results showed that obesity does not increase UI risk at 24 months (OR 1.13, 95% CI [0.74, 1.72], P=0.58).
This is the first study to include obesity as the primary independent variable.
Outcomes indicate that obesity (BMI ≥ 30) may increase the UI risk at 12 and 24 months after RLRP.
Well-designed randomized controlled trials with strict control of confounders are needed to make results comparable.
American Psychological Association (APA)
Wei, Yong& Wu, Yu-Peng& Lin, Min-Yi& Chen, Shao-Hao& Lin, Yun-Zhi& Li, Xiao-Dong…[et al.]. 2018. Impact of Obesity on Long-Term Urinary Incontinence after Radical Prostatectomy: A Meta-Analysis. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1129021
Modern Language Association (MLA)
Wei, Yong…[et al.]. Impact of Obesity on Long-Term Urinary Incontinence after Radical Prostatectomy: A Meta-Analysis. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1129021
American Medical Association (AMA)
Wei, Yong& Wu, Yu-Peng& Lin, Min-Yi& Chen, Shao-Hao& Lin, Yun-Zhi& Li, Xiao-Dong…[et al.]. Impact of Obesity on Long-Term Urinary Incontinence after Radical Prostatectomy: A Meta-Analysis. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1129021
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1129021