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Probable RBD Associates with the Development of RLS in Parkinson’s Disease: A Cross-Sectional Study
Joint Authors
Qu, Yewei
Zhang, Lu
Shen, Dongfang
Zhang, Wangzikang
Zhang, Mingsha
Pan, Yujun
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objectives.
We aimed to investigate the prevalence of restless leg syndrome (RLS) and exploring the contributing factors that affect the development of RLS in Parkinson’s disease (PD) patients.
Methods.
A cross-sectional study was conducted consisting of 178 consecutive PD patients from our hospital between October 2015 and August 2016.
We divided the participants into two groups, which were PD with RLS and PD with non-RLS.
Then, we recorded their demographics and clinical data to draw a comparison between PD with RLS and PD with non-RLS.
Results.
23 (12.92%) were diagnosed with RLS among all the enrolled PD patients.
Unified Parkinson’s Disease Rating Scale III (UPDRS III) and Hamilton Depression Scale (HAMD) scores, probable rapid eye movement sleep behavior disorder (PRBD), and daily levodopa equivalent dose (LED) in the PD with the RLS group were significantly different from those in the PD with the non-RLS group.
Daily LED and the scores of UPDRS III and HAMD in PD patients with RLS were all higher than those in PD patients with non-RLS.
PRBD, daily LED, and HAMD scores were significantly independent factors contributing to the development of RLS (OR=4.678, 95% CI 1.372~15.944, P=0.014; OR=1.003, 95% CI 1.001~1.005, P=0.019; OR=1.094, 95% CI 1.002~1.193, P=0.045).
The severity of RLS was positively correlated with the duration of PD and daily LED (r=0.438, P=0.036; r=0.637, P=0.001).
Conclusion.
PRBD existence, daily LED, and HAMD scores are independent factors for developing RLS in PD patients.
PRBD existence is firstly proposed as an independent factor in developing RLS among PD patients.
RLS severity in PD patients are positively associated with the duration of PD and daily LED.
American Psychological Association (APA)
Qu, Yewei& Zhang, Lu& Shen, Dongfang& Zhang, Wangzikang& Zhang, Mingsha& Pan, Yujun. 2019. Probable RBD Associates with the Development of RLS in Parkinson’s Disease: A Cross-Sectional Study. Behavioural Neurology،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1129022
Modern Language Association (MLA)
Qu, Yewei…[et al.]. Probable RBD Associates with the Development of RLS in Parkinson’s Disease: A Cross-Sectional Study. Behavioural Neurology No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1129022
American Medical Association (AMA)
Qu, Yewei& Zhang, Lu& Shen, Dongfang& Zhang, Wangzikang& Zhang, Mingsha& Pan, Yujun. Probable RBD Associates with the Development of RLS in Parkinson’s Disease: A Cross-Sectional Study. Behavioural Neurology. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1129022
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1129022