Quantification of Multifunctional Dipeptide YA from Oyster Hydrolysate for Quality Control and Efficacy Evaluation
Joint Authors
Choi, Yeung-Joon
Kang, Sang Soo
Lu, Ciyong
Xie, Cheng-Liang
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-24
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
YA is an angiotensin-I-converting enzyme- (ACE-) inhibitory peptide from oyster hydrolysate with antihypertensive activity.
Its antioxidant and anti-inflammatory activity were investigated in this study.
YA can dose-dependently quench DPPH and ABTS radical and inhibit lipopolysaccharide-induced nitric oxide in RAW 264.7 cells.
YA is a multifunctional peptide and was selected as an indicator for quality control and efficacy evaluation of oyster hydrolysate.
A practical HPLC/UV assay for YA quantification was developed and validated.
It was proved to be accurate and reliable, according to parameters such as specificity, linearity, precision, and accuracy.
The quantity results of YA showed that the stage of enzymatic hydrolysis was a critical control point for quality control; the efficacy of oyster hydrolysate can be enhanced after digested in the gastrointestinal tract due to the release of YA by brush border peptidases.
Therefore, YA from oyster hydrolysate is a potential bioactive ingredient for functional foods to combat hypertension.
American Psychological Association (APA)
Xie, Cheng-Liang& Kang, Sang Soo& Lu, Ciyong& Choi, Yeung-Joon. 2018. Quantification of Multifunctional Dipeptide YA from Oyster Hydrolysate for Quality Control and Efficacy Evaluation. BioMed Research International،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1129150
Modern Language Association (MLA)
Xie, Cheng-Liang…[et al.]. Quantification of Multifunctional Dipeptide YA from Oyster Hydrolysate for Quality Control and Efficacy Evaluation. BioMed Research International No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1129150
American Medical Association (AMA)
Xie, Cheng-Liang& Kang, Sang Soo& Lu, Ciyong& Choi, Yeung-Joon. Quantification of Multifunctional Dipeptide YA from Oyster Hydrolysate for Quality Control and Efficacy Evaluation. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1129150
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1129150