Biochemical Stimulus-Based Strategies for Meniscus Tissue Engineering and Regeneration
Joint Authors
Guo, Weimin
Wang, Ai-Yuan
Guo, Quan-Yi
Wang, Yu
Yuan, Zhiguo
Sui, Xiang
Chen, Mingxue
Wang, Mingjie
Gao, Shunag
Hao, Chunxiang
Shen, Shi
Zhang, Zengzeng
Wang, Zhenyong
Wang, Zehao
Li, Xu
Jing, Xiaoguang
Zhang, Xueliang
Zhang, Yu
Peng, Jiang
Liu, Shuyun
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-17
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Meniscus injuries are very common and still pose a challenge for the orthopedic surgeon.
Meniscus injuries in the inner two-thirds of the meniscus remain incurable.
Tissue-engineered meniscus strategies seem to offer a new approach for treating meniscus injuries with a combination of seed cells, scaffolds, and biochemical or biomechanical stimulation.
Cell- or scaffold-based strategies play a pivotal role in meniscus regeneration.
Similarly, biochemical and biomechanical stimulation are also important.
Seed cells and scaffolds can be used to construct a tissue-engineered tissue; however, stimulation to enhance tissue maturation and remodeling is still needed.
Such stimulation can be biomechanical or biochemical, but this review focuses only on biochemical stimulation.
Growth factors (GFs) are one of the most important forms of biochemical stimulation.
Frequently used GFs always play a critical role in normal limb development and growth.
Further understanding of the functional mechanism of GFs will help scientists to design the best therapy strategies.
In this review, we summarize some of the most important GFs in tissue-engineered menisci, as well as other types of biological stimulation.
American Psychological Association (APA)
Chen, Mingxue& Guo, Weimin& Gao, Shunag& Hao, Chunxiang& Shen, Shi& Zhang, Zengzeng…[et al.]. 2018. Biochemical Stimulus-Based Strategies for Meniscus Tissue Engineering and Regeneration. BioMed Research International،Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1129169
Modern Language Association (MLA)
Chen, Mingxue…[et al.]. Biochemical Stimulus-Based Strategies for Meniscus Tissue Engineering and Regeneration. BioMed Research International No. 2018 (2018), pp.1-15.
https://search.emarefa.net/detail/BIM-1129169
American Medical Association (AMA)
Chen, Mingxue& Guo, Weimin& Gao, Shunag& Hao, Chunxiang& Shen, Shi& Zhang, Zengzeng…[et al.]. Biochemical Stimulus-Based Strategies for Meniscus Tissue Engineering and Regeneration. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1129169
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1129169