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Experimental Nanopulse Ablation of Multiple Membrane Parasite on Ex Vivo Hydatid Cyst
Joint Authors
Chen, Xinhua
Zhang, RuiQing
Wen, Hao
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The impact of ultrashort nanopulse on cellular membrane is of biological significance and thus has been studied intensively.
Different from cell study, this ex vivo study aims to investigate the biological effects of nanosecond pulsed electric field (nsPEF) on an independent multimembrane parasite, human hydatid cyst, to observe the unique influence of nanopulse on macromembrane structure, permeabilization, and biochemistry.
The 300 ns nsPEF was delivered on an experimental model of single human hydatid cyst ex vivo with eight different parameters.
Then pathological changes during 7 days of 48 parasite cysts were followed up after nsPEF.
The laminated layer, the germinal layer, the protoscolex, and cyst fluid were evaluated by the morphological, pathological, and biochemical measurements.
The parameter screening found that nsPEF can damage hydatid cyst effectively when the field strength is higher than 14 kV/cm.
When nsPEF is higher than 29 kV/cm, nsPEF destroy hydatid cyst completely by collapsing the germinal layer, destructing protoscolices, and exhausting the nutrition.
American Psychological Association (APA)
Chen, Xinhua& Zhang, RuiQing& Wen, Hao. 2018. Experimental Nanopulse Ablation of Multiple Membrane Parasite on Ex Vivo Hydatid Cyst. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1129196
Modern Language Association (MLA)
Chen, Xinhua…[et al.]. Experimental Nanopulse Ablation of Multiple Membrane Parasite on Ex Vivo Hydatid Cyst. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1129196
American Medical Association (AMA)
Chen, Xinhua& Zhang, RuiQing& Wen, Hao. Experimental Nanopulse Ablation of Multiple Membrane Parasite on Ex Vivo Hydatid Cyst. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1129196
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1129196