Changes in Serum Electrolytes, ECG, and Baroreflex Sensitivity during Combined Pituitary Stimulation Test
Joint Authors
Kim, Sungsu
Kwak, Choong Hwan
Jung, Jaehoon
Baek, Jong Ha
Jung, Jung Hwa
Park, Ki-Jong
Kim, Kyongyoung
Kim, Soo Kyoung
Kang, Dawon
Hahm, Jong Ryeal
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-09
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The mechanisms by which hypoglycemia increases cardiovascular mortality remain unclear.
The aim of the study is to investigate changes in serum electrolytes, norepinephrine concentrations, electrocardiography, and baroreflex sensitivity (BRS) and associations between corrected QT (QTc) intervals and the changes in serum electrolytes during combined pituitary stimulation test (CPST).
We recruited the subjects who were admitted to the Gyeongsang National University Hospital to undergo CPST between September 2013 and December 2014.
Participants were 12 patients suspected of having hypopituitarism.
Among 12 patients, cardiac arrhythmia in two patients occurred during hypoglycemia.
There were significant differences in serum levels of potassium (P<0.001), sodium (P=0.003), chloride (P=0.002), and calcium (P=0.017) at baseline, hypoglycemia, and 30 and 120 minutes after hypoglycemia.
Also, there was a significant increase in heart rate (P=0.004), corrected QT (QTc) interval (P=0.008), QRS duration (P=0.021), and BRS (P=0.005) at hypoglycemia, compared to other time points during CPST.
There was a positive association between QTc intervals and serum sodium levels (P<0.001) in 10 patients who did not develop arrhythmia during CPST.
This study showed that there were significant changes in serum levels of potassium, sodium, chloride, and calcium, as well as heart rate, QTc interval, QRSd, and BRS during CPST.
It was revealed that QTc intervals had a significant association with concentrations of sodium.
American Psychological Association (APA)
Kim, Sungsu& Kwak, Choong Hwan& Jung, Jaehoon& Baek, Jong Ha& Jung, Jung Hwa& Park, Ki-Jong…[et al.]. 2018. Changes in Serum Electrolytes, ECG, and Baroreflex Sensitivity during Combined Pituitary Stimulation Test. BioMed Research International،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1129292
Modern Language Association (MLA)
Kim, Sungsu…[et al.]. Changes in Serum Electrolytes, ECG, and Baroreflex Sensitivity during Combined Pituitary Stimulation Test. BioMed Research International No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1129292
American Medical Association (AMA)
Kim, Sungsu& Kwak, Choong Hwan& Jung, Jaehoon& Baek, Jong Ha& Jung, Jung Hwa& Park, Ki-Jong…[et al.]. Changes in Serum Electrolytes, ECG, and Baroreflex Sensitivity during Combined Pituitary Stimulation Test. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1129292
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1129292