Temporal Change of Interleukin-6, C-Reactive Protein, and Skin Temperature after Total Knee Arthroplasty Using Triclosan-Coated Sutures
Joint Authors
Shih, Hsin-Nung
Lin, Shih-Jie
Huang, Tsan-Wen
Peng, Kuo-Ti
Chang, Fu-Chun
Lee, Mel S.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-15
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The risk of surgical site infections (SSIs) after total knee arthroplasty (TKA) can never be eliminated.
Antimicrobial sutures containing triclosan have been used to decrease SSIs, but whether triclosan-coated sutures are effective with TKA is unclear.
Between 2011 and 2012, 102 patients randomly assigned to a triclosan or a control group were prospectively assessed.
The incidence of SSI within 3 months of surgery, length of hospital stay, pain scale, functional scores, wound condition, and serum inflammatory markers during hospitalization and within 3 months postoperatively were compared.
At the final follow-up, there were 2 patients with superficial infections (3.9%) in the control group but none in the triclosan group.
Lower serum IL-6 was detected in the triclosan group at 4 weeks and 3 months.
The local skin temperature of the knees—recorded at 3 months using infrared thermography—was lower in the triclosan group than in the control group.
More precise analytical measurements are needed to investigate local and systemic complications, especially in the early subclinical stage.
This prospective, randomized, open-label clinical trial is in the public registry: ClinicalTrials.gov (NCT02533492).
American Psychological Association (APA)
Lin, Shih-Jie& Chang, Fu-Chun& Huang, Tsan-Wen& Peng, Kuo-Ti& Shih, Hsin-Nung& Lee, Mel S.. 2018. Temporal Change of Interleukin-6, C-Reactive Protein, and Skin Temperature after Total Knee Arthroplasty Using Triclosan-Coated Sutures. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1129521
Modern Language Association (MLA)
Lin, Shih-Jie…[et al.]. Temporal Change of Interleukin-6, C-Reactive Protein, and Skin Temperature after Total Knee Arthroplasty Using Triclosan-Coated Sutures. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1129521
American Medical Association (AMA)
Lin, Shih-Jie& Chang, Fu-Chun& Huang, Tsan-Wen& Peng, Kuo-Ti& Shih, Hsin-Nung& Lee, Mel S.. Temporal Change of Interleukin-6, C-Reactive Protein, and Skin Temperature after Total Knee Arthroplasty Using Triclosan-Coated Sutures. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1129521
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1129521