Blood Transfusion Frequency and Indications in Yemeni Children with Sickle Cell Disease
Joint Authors
Al-Saqladi, Abdul-Wahab M.
Maddi, Dikra M.
Al-Sadeeq, Aida H.
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Blood transfusion is an essential component in the care of patients with sickle cell disease (SCD), but it might be associated with serious acute and delayed complications.
This study was aimed to describe red cell transfusion patterns and indications among hospitalized SCD children in a low-resource setting.
Patients and Methods.
A retrospective, descriptive study of all children (≤16 years) with SCD who received blood transfusion therapy during their hospital admissions in the pediatric department at Al-Sadaqa Teaching Hospital in Aden, Yemen, for a period of one year.
Results.
Out of 217 hospitalized children with SCD, 169 (77.9%) were transfused and received 275 RBC transfusion episodes.
The mean age of transfused children was 6.9 ± 4.6 years and 103 (60.9%) were males, with a male/female ratio of 1.6 : 1 (p=0.004).
Hemoglobin (Hb) levels were significantly lower in the transfused than in the nontransfused (Hb 5.5 ± 1.5 vs.
7.7 ± 1.5 g/dL, p=0.03).
Pretransfusion Hb levels were ˂7.0 g/dL in 86.2% and ˂5.0 g/dL in 39.3% of patients.
Single transfusion was given to 122 (72.2%) and 5 or more transfusions in 9 (4.15%) of patients on different occasions.
Simple (top-up) transfusion was used in all transfusion events.
Commonest indications for transfusion were anemic crises (41.1%), vasoocclusive crises (VOC) (13.8%), VOC with anemic event (11.3%), acute chest syndrome (8.7%), and stroke (7.3%).
Conclusion.
Intermittent blood transfusion remains a common practice for the management of children with acute SCD complications.
Main indications were acute anemic crises, severe pain crises, ACS, and stroke.
In limited resource settings, such as Yemen, conservative transfusion policy appears to be appropriate.
American Psychological Association (APA)
Al-Saqladi, Abdul-Wahab M.& Maddi, Dikra M.& Al-Sadeeq, Aida H.. 2020. Blood Transfusion Frequency and Indications in Yemeni Children with Sickle Cell Disease. Anemia،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1129736
Modern Language Association (MLA)
Al-Saqladi, Abdul-Wahab M.…[et al.]. Blood Transfusion Frequency and Indications in Yemeni Children with Sickle Cell Disease. Anemia No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1129736
American Medical Association (AMA)
Al-Saqladi, Abdul-Wahab M.& Maddi, Dikra M.& Al-Sadeeq, Aida H.. Blood Transfusion Frequency and Indications in Yemeni Children with Sickle Cell Disease. Anemia. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1129736
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1129736