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Direct Oral Anticoagulants in Cirrhotic Patients: Current Evidence and Clinical Observations
Joint Authors
Elhosseiny, Sherif
Al Moussawi, Hassan
Chalhoub, Jean M.
Lafferty, James
Deeb, Liliane
Source
Canadian Journal of Gastroenterology and Hepatology
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-08
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The introduction of Direct Oral Anticoagulants (DOACs) to the pharmaceutical market provided patients and clinicians with novel convenient and safe options of anticoagulation.
The use of this class of medications is currently limited to venous thromboembolic therapy and prophylaxis, in addition to stroke prophylaxis in patients with nonvalvular atrial fibrillation.
Despite their altered hemostasis, patients with cirrhosis are thought to be in a procoagulant state and thus prone to thrombus formation.
Patients with cirrhosis might benefit from the convenience of DOACs; however, the medical literature includes limited data on the efficacy and safety of DOACs in this special patient population.
The aim of this review is to summarize the current evidence for anticoagulation options in patients with cirrhosis and their safety profile.
American Psychological Association (APA)
Elhosseiny, Sherif& Al Moussawi, Hassan& Chalhoub, Jean M.& Lafferty, James& Deeb, Liliane. 2019. Direct Oral Anticoagulants in Cirrhotic Patients: Current Evidence and Clinical Observations. Canadian Journal of Gastroenterology and Hepatology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1129841
Modern Language Association (MLA)
Elhosseiny, Sherif…[et al.]. Direct Oral Anticoagulants in Cirrhotic Patients: Current Evidence and Clinical Observations. Canadian Journal of Gastroenterology and Hepatology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1129841
American Medical Association (AMA)
Elhosseiny, Sherif& Al Moussawi, Hassan& Chalhoub, Jean M.& Lafferty, James& Deeb, Liliane. Direct Oral Anticoagulants in Cirrhotic Patients: Current Evidence and Clinical Observations. Canadian Journal of Gastroenterology and Hepatology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1129841
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1129841