The Association between Red Blood Cell Distribution Width and Mortality in Critically Ill Patients with Acute Kidney Injury
Joint Authors
Wang, Benji
Gong, Yuqiang
Ying, Binyu
Cheng, Bihuan
Lu, Huaya
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Several investigators have sought risk factors for mortality in acute kidney injury (AKI).
However, no epidemiological studies have investigated the impact of red blood cell distribution width (RDW) on prognosis for critically ill patients with AKI.
The aim of this study was to investigate the association of RDW with mortality in these patients.
Methods.
We analyzed data from the MIMIC-III.
RDW was measured upon ICU admission.
The association between RDW and mortality of AKI was determined using a multivariate logistic regression and was expressed as the adjusted odds ratio with associated 95% confidence interval (CI).
We also conducted subgroup analyses to determine the consistency of this association.
Results.
A total of 14,078 critically ill patients with AKI were eligible for this analysis.
In multivariate analysis, adjusted for age and gender and compared with the reference group (RDW 11.1-13.4%) related to hospital mortality, the adjusted ORs (95% CIs) for RDW levels 13.5-14.3%, 14.4-15.6%, and 15.7-21.2% were 1.22 (1.05, 1.43), 1.56 (1.35, 1.81), and 2.66 (2.31, 3.06), respectively.
After adjusting for confounding factors, with high RDW linked to an increase in mortality (RDW 15.7-21.2% versus 11.1-13.4%: OR, 1.57; 95% CI, 1.22 to 2.01; P trend <0.0001).
A similar trend was observed for 30-day mortality.
Conclusions.
RDW appeared to be an independent prognostic marker in critically ill patients with AKI and higher RDW was associated with increased risk of mortality in these patients.
American Psychological Association (APA)
Wang, Benji& Lu, Huaya& Gong, Yuqiang& Ying, Binyu& Cheng, Bihuan. 2018. The Association between Red Blood Cell Distribution Width and Mortality in Critically Ill Patients with Acute Kidney Injury. BioMed Research International،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1129958
Modern Language Association (MLA)
Wang, Benji…[et al.]. The Association between Red Blood Cell Distribution Width and Mortality in Critically Ill Patients with Acute Kidney Injury. BioMed Research International No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1129958
American Medical Association (AMA)
Wang, Benji& Lu, Huaya& Gong, Yuqiang& Ying, Binyu& Cheng, Bihuan. The Association between Red Blood Cell Distribution Width and Mortality in Critically Ill Patients with Acute Kidney Injury. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1129958
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1129958