Elevated Blood Urea Nitrogen-to-Serum Albumin Ratio as a Factor That Negatively Affects the Mortality of Patients with Hospital-Acquired Pneumonia
Joint Authors
Feng, Ding-Yun
Zhou, Yu-Qi
Zou, Xiao-Ling
Zhou, Mi
Yang, Hai-Ling
Chen, Xiao-Xia
Zhang, Tian-Tuo
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
This study aimed to evaluate the factors that affect 30-day mortality of patients with HAP.
The data used in this study were collected from all HAP occurred in our hospital between January 2014 and December 2017.
A total of 1158 cases were included.
150 (13.0%) of whom died within 30 days.
This reported mortality identified by the univariate Cox regression analysis is found to have been affected by the following factors: age greater than 70 years, presence of diabetes mellitus and chronic obstructive pulmonary disease, gastric tube intubation, administration of proton-pump inhibitor, blood albumin level less than 30 g/l, elevated neutrophil-to-lymphocyte ratio, antibiotics therapy in the preceding 90 days, intensive care unit (ICU) admission, blood lymphocyte count less than 0.8 × 109/L, elevated blood urea nitrogen/albumin (BUN/ALB) level, and presence of multidrug-resistant (MDR) pathogens.
In the second multivariate analysis, administration of proton-pump inhibitor, administration of antibiotics in the preceding 90 days, ICU admission, blood lymphocyte count less than 0.8 × 109/L, elevated BUN/ALB level, and presence of MDR pathogens were still associated with 30-day mortality.
The area under the receiver operating characteristic curves in the BUN/ALB predicting 30-day mortality due to HAP was 0.685.
A high BUN/ALB was significantly associated with a worse survival than a low BUN/ALB P<0.001.
Therefore, an elevated BUN/ALB level is a risk factor for mortality on patients with HAP.
American Psychological Association (APA)
Feng, Ding-Yun& Zhou, Yu-Qi& Zou, Xiao-Ling& Zhou, Mi& Yang, Hai-Ling& Chen, Xiao-Xia…[et al.]. 2019. Elevated Blood Urea Nitrogen-to-Serum Albumin Ratio as a Factor That Negatively Affects the Mortality of Patients with Hospital-Acquired Pneumonia. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1130006
Modern Language Association (MLA)
Feng, Ding-Yun…[et al.]. Elevated Blood Urea Nitrogen-to-Serum Albumin Ratio as a Factor That Negatively Affects the Mortality of Patients with Hospital-Acquired Pneumonia. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1130006
American Medical Association (AMA)
Feng, Ding-Yun& Zhou, Yu-Qi& Zou, Xiao-Ling& Zhou, Mi& Yang, Hai-Ling& Chen, Xiao-Xia…[et al.]. Elevated Blood Urea Nitrogen-to-Serum Albumin Ratio as a Factor That Negatively Affects the Mortality of Patients with Hospital-Acquired Pneumonia. Canadian Journal of Infectious Diseases and Medical Microbiology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1130006
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130006