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Direct Intrahepatic Portocaval Shunt for Sinusoidal Obstruction Syndrome Associated with Hepatotoxicity of Pyrrolizidine Alkaloids
Joint Authors
Luo, ShiHua
Chu, Jianguo
Huang, He
Yao, Kechun
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-13
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
We retrospectively identified 89 consecutive patients from January 2004 to January 2012 to investigate efficacy of direct intrahepatic portocaval shunt (DIPS) combined with inferior vena cava (IVC) stenting for sinusoidal obstruction syndrome (SOS) associated with hepatotoxicity of pyrrolizidine alkaloids.
Indications for treatment were variceal hemorrhage and/or refractory ascites.
Patients were treated with DIPS plus IVC stenting (group A, n=68) or DIPS alone (group B, n=21).
A technical success rate of 100% was obtained in all 89 patients, and there were no early procedure-related adverse events or 30-day mortality.
Mean portosystemic gradient decreased in both groups.
Changes in aspartate and alanine aminotransferases and total bilirubin did not differ between the groups.
Ascites disappeared in group A but was not obvious in group B until IVC stenting.
During follow-up, recurrent bleeding and ascites and incidence of hepatic encephalopathy did not differ between the groups.
The 1-, 3-, and 5-year survival rate was 98, 89.59, and 80%, respectively.
Satisfactory clinical results were obtained for combined DIPS and IVC stenting for SOS associated with pyrrolizidine-alkaloid-related decompensated cirrhosis.
American Psychological Association (APA)
Luo, ShiHua& Chu, Jianguo& Huang, He& Yao, Kechun. 2018. Direct Intrahepatic Portocaval Shunt for Sinusoidal Obstruction Syndrome Associated with Hepatotoxicity of Pyrrolizidine Alkaloids. BioMed Research International،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1130039
Modern Language Association (MLA)
Luo, ShiHua…[et al.]. Direct Intrahepatic Portocaval Shunt for Sinusoidal Obstruction Syndrome Associated with Hepatotoxicity of Pyrrolizidine Alkaloids. BioMed Research International No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1130039
American Medical Association (AMA)
Luo, ShiHua& Chu, Jianguo& Huang, He& Yao, Kechun. Direct Intrahepatic Portocaval Shunt for Sinusoidal Obstruction Syndrome Associated with Hepatotoxicity of Pyrrolizidine Alkaloids. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1130039
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130039