Methicillin-Resistant Staphylococcus aureus Nasal Colonization among Healthcare Workers at Kampala International University Teaching Hospital, Southwestern Uganda
Joint Authors
Bazira, Joel
Abimana, Justus B.
Kato, Charles D.
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Whereas Staphylococcus aureus is a pathogen, it colonizes healthy people as normal flora without causing any symptoms or illness.
Probably because of greater exposure, healthcare workers (HCWs) are more colonized, serving as reservoir for endogenous infections as well as dissemination.
In developing countries including Uganda, there is scarcity of the literature on S.
aureus carriage among HCWs, making infection control difficult.
This study aimed at determining the nasal carriage rate and comparing the antimicrobial susceptibility profiles of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible Staphylococcus aureus (MSSA) isolates from HCWs of Kampala International University Teaching Hospital.
Nasal swab specimens from HCWs were screened for MRSA using both phenotypic and genotypic methods.
Antimicrobial susceptibility testing of the MRSA and MSSA isolates was performed using the Kirby–Bauer disc diffusion method.
Out of the 97 participants, 28 (28.8%) participants were nasal carriers of S.
aureus of which 13 (46.4%) were phenotypically MRSA (resistant to cefoxitin) and 8 (28.6%) were genotypically MRSA (had mecA gene).
Only 6 isolates of the 13 isolates (46%) which showed resistance to cefoxitin had mecA gene detectable while 2 (13.3%) of the 15 cefoxitin susceptible isolates were found to carry mecA gene.
The study thus shows that methicillin resistance in S.
aureus may not only be determined by mecA gene.
American Psychological Association (APA)
Abimana, Justus B.& Kato, Charles D.& Bazira, Joel. 2019. Methicillin-Resistant Staphylococcus aureus Nasal Colonization among Healthcare Workers at Kampala International University Teaching Hospital, Southwestern Uganda. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1130060
Modern Language Association (MLA)
Abimana, Justus B.…[et al.]. Methicillin-Resistant Staphylococcus aureus Nasal Colonization among Healthcare Workers at Kampala International University Teaching Hospital, Southwestern Uganda. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1130060
American Medical Association (AMA)
Abimana, Justus B.& Kato, Charles D.& Bazira, Joel. Methicillin-Resistant Staphylococcus aureus Nasal Colonization among Healthcare Workers at Kampala International University Teaching Hospital, Southwestern Uganda. Canadian Journal of Infectious Diseases and Medical Microbiology. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1130060
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130060