State-of-the-Art Preclinical Photoacoustic Imaging in Oncology: Recent Advances in Cancer Theranostics
Joint Authors
Gargiulo, Sara
Albanese, Sandra
Mancini, Marcello
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-24, 24 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-30
Country of Publication
Egypt
No. of Pages
24
Main Subjects
Abstract EN
The optical imaging plays an increasing role in preclinical studies, particularly in cancer biology.
The combined ultrasound and optical imaging, named photoacoustic imaging (PAI), is an emerging hybrid technique for real-time molecular imaging in preclinical research and recently expanding into clinical setting.
PAI can be performed using endogenous contrast, particularly from oxygenated and deoxygenated hemoglobin and melanin, or exogenous contrast agents, sometimes targeted for specific biomarkers, providing comprehensive morphofunctional and molecular information on tumor microenvironment.
Overall, PAI has revealed notable opportunities to improve knowledge on tumor pathophysiology and on the biological mechanisms underlying therapy.
The aim of this review is to introduce the principles of PAI and to provide a brief overview of current PAI applications in preclinical research, highlighting also on recent advances in clinical translation for cancer diagnosis, staging, and therapy.
American Psychological Association (APA)
Gargiulo, Sara& Albanese, Sandra& Mancini, Marcello. 2019. State-of-the-Art Preclinical Photoacoustic Imaging in Oncology: Recent Advances in Cancer Theranostics. Contrast Media & Molecular Imaging،Vol. 2019, no. 2019, pp.1-24.
https://search.emarefa.net/detail/BIM-1130264
Modern Language Association (MLA)
Gargiulo, Sara…[et al.]. State-of-the-Art Preclinical Photoacoustic Imaging in Oncology: Recent Advances in Cancer Theranostics. Contrast Media & Molecular Imaging No. 2019 (2019), pp.1-24.
https://search.emarefa.net/detail/BIM-1130264
American Medical Association (AMA)
Gargiulo, Sara& Albanese, Sandra& Mancini, Marcello. State-of-the-Art Preclinical Photoacoustic Imaging in Oncology: Recent Advances in Cancer Theranostics. Contrast Media & Molecular Imaging. 2019. Vol. 2019, no. 2019, pp.1-24.
https://search.emarefa.net/detail/BIM-1130264
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130264