Application of Contrast-Enhanced Ultrasound (CEUS) in Lymphomatous Lymph Nodes: A Comparison between PETCT and Contrast-Enhanced CT
Joint Authors
Ma, Xuelei
Ling, Wenwu
Xia, Fan
Zhang, Yifan
Zhu, Chenjing
He, Jialing
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
We described imaging characteristics of different types of lymphomas using contrast-enhanced ultrasound (CEUS) and summarized some simple criteria to distinguish between normal lymph nodes and lymphomatous lymph nodes for clinical diagnosis.
Materials and methods.
Sixty-one lymphoma patients from 2014 to 2015 with 140 suspicious lymph nodes, who had been confirmed by histology and underwent chemotherapy, were enrolled in our study.
The responses to chemotherapy were recorded by PET/CT, contrast-enhanced CT, or CEUS.
Results.
We summarized the CEUS enhancement patterns as two types when detecting lymphomatous lymph nodes, which could be the specific diagnostic criteria: (1) rapid well-distributed hyperenhancement, with 83.1% lesions exhibiting a fast-in hyperenhancement pattern in the arterial phase, and (2) rapid heterogeneous hyperenhancement, with 16.9% lesions exhibiting heterogeneous in the arterial phase.
Particularly, we found that all the suspicious lesions of indolent lymphomas were rapid well-distributed hyperenhancement.
CEUS successfully identified 117 lymphomatous lymph nodes, while PET/CT and contrast-enhanced CT detected 124 and 113 lymphomatous lymph nodes, respectively.
CEUS had an accuracy of 83.57%, and the accuracy of PET/CT and contrast-enhanced CT was 88.57% and 80.71%, respectively (p=0.188).
The false-negative rate was 16.43%, 11.43%, and 19.29%, respectively (p=0.188).
Conclusion.
CEUS could be a useful tool in detecting lymphomatous nodes.
A rapid well-distributed hyperenhancement pattern in CEUS could be a useful diagnostic criterion in both aggressive lymphoma and indolent lymphoma.
These results can help us distinguish between lymphomatous and benign lymph nodes and make better diagnostic and therapeutic decisions.
American Psychological Association (APA)
Ma, Xuelei& Ling, Wenwu& Xia, Fan& Zhang, Yifan& Zhu, Chenjing& He, Jialing. 2019. Application of Contrast-Enhanced Ultrasound (CEUS) in Lymphomatous Lymph Nodes: A Comparison between PETCT and Contrast-Enhanced CT. Contrast Media & Molecular Imaging،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1130294
Modern Language Association (MLA)
Ma, Xuelei…[et al.]. Application of Contrast-Enhanced Ultrasound (CEUS) in Lymphomatous Lymph Nodes: A Comparison between PETCT and Contrast-Enhanced CT. Contrast Media & Molecular Imaging No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1130294
American Medical Association (AMA)
Ma, Xuelei& Ling, Wenwu& Xia, Fan& Zhang, Yifan& Zhu, Chenjing& He, Jialing. Application of Contrast-Enhanced Ultrasound (CEUS) in Lymphomatous Lymph Nodes: A Comparison between PETCT and Contrast-Enhanced CT. Contrast Media & Molecular Imaging. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1130294
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130294