Highly Biocompatible Nanoparticles of Au@Fluorescent Polymers as Novel Contrast Agent for In Vivo Bimodality NIR FluorescenceCT Imaging
Joint Authors
Wang, Guannan
Zhang, Mengshu
Liu, Jinlei
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-10
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
In this work, one kind of biocompatible and all-in-one dual-modal nanoprobe, based on Au nanoparticles and NIR emissive semiconducting fluorescence polymers, was developed by the one-step solvent-mediated self-assembly method for in vivo X-ray computed tomography (CT) and fluorescence bioimaging for the first time.
After preparation, a series of comprehensive evaluations were performed, and the nanoprobe exhibited smart size and modification, good compatibility, inducement of autophagy, long blood circulation, unconspicuous in vivo toxicity, and excellent fluorescence/CT imaging effects.
Overall, the studies in this work assuredly indicate that the synthesized Au@FP nanoparticles as a noninvasive contrast agent is suitable for in vivo fluorescence/X-ray CT bimodality biomedical imaging and diagnosis.
American Psychological Association (APA)
Zhang, Mengshu& Liu, Jinlei& Wang, Guannan. 2019. Highly Biocompatible Nanoparticles of Au@Fluorescent Polymers as Novel Contrast Agent for In Vivo Bimodality NIR FluorescenceCT Imaging. Contrast Media & Molecular Imaging،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1130358
Modern Language Association (MLA)
Zhang, Mengshu…[et al.]. Highly Biocompatible Nanoparticles of Au@Fluorescent Polymers as Novel Contrast Agent for In Vivo Bimodality NIR FluorescenceCT Imaging. Contrast Media & Molecular Imaging No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1130358
American Medical Association (AMA)
Zhang, Mengshu& Liu, Jinlei& Wang, Guannan. Highly Biocompatible Nanoparticles of Au@Fluorescent Polymers as Novel Contrast Agent for In Vivo Bimodality NIR FluorescenceCT Imaging. Contrast Media & Molecular Imaging. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1130358
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130358